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Effects of Exercise on Energy Intake-Prescription of Resistance Exercise

Effects of Acute Resistance Exercise With Varying Training Volume and Rest Intervals Under Equal Load on Appetite Control, Food Reward, and Energy Intake: a Five-arm Crossover Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06223282
Enrollment
18
Registered
2024-01-25
Start date
2022-10-28
Completion date
2023-03-31
Last updated
2024-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating Behavior, Food Reward

Brief summary

Healthy young males will complete five trials in a randomized crossover counter-balanced order, including three different inter-set rest of resistance exercise in equal training volume, one repeated until failure and sedentary control. During each trial, blood samples will be collected. The investigators hypothesized that different inter-set rest and training volume would affect subjective appetite and energy intake.

Interventions

OTHERshort inter-set rest resistance exercise

Subjects in short inter-set rest trial performed 3 sets per exercise, 7 repetitions with load of 70%-1RM with 60 sec of rest between sets.

OTHERmedium inter-set rest

Subjects in medium inter-set rest trial performed 3 sets per exercise, 7 repetitions with load of 70%-1RM with 120 sec of rest between sets.

OTHERlong inter-set rest

Subjects in long inter-set rest trial performed 3 sets per exercise, 7 repetitions with load of 70%-1RM with 180 sec of rest between sets.

OTHERmedium inter-set rest with failure

Subjects in long inter-set rest trial performed 3 sets per exercise, repeated to failure with load of 70%-1RM with 120 sec of rest between sets.

Sponsors

National Taiwan Normal University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
20 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Age: 20-30 * Healthy male

Exclusion criteria

* No acute or chronic musculoskeletal symptoms * Smoking * Alcohol or drug abuse * Failure to conduct resistance exercise

Design outcomes

Primary

MeasureTime frameDescription
Subjective appetite4-hour during each study interventionThe appetite perceptions were obtained through a 0-100 mm visual analog scale. The variables assessed included perceptions of hunger (i.e., How hungry do you feel?), satisfaction (i.e., How satisfied do you feel?), fullness (i.e., How full do you feel?), prospective food consumption (i.e., How much do you think you can eat?), and nausea (i.e., How nauseous do you feel?), with 0 indicating not at all and 100 signifying extremely..
Change in acyl-Ghrelin4-hour during each study interventionacyl-Ghrelin in pg/mL
Change in total-Ghrelin4-hour during each study interventiontotal-Ghrelin in pg/mL
Change in PYY4-hour during each study interventionPYY in pg/mL
Change in active-GLP-14-hour during each study interventionactive-GLP-1 in pg/mL
Change in total-GLP-14-hour during each study interventiontotal-GLP-1 in pg/mL
Change in lactate4-hour during each study interventioninsulin in mmol/L

Secondary

MeasureTime frameDescription
Change in TG4 hours during each study interventionTG in mg/dL
Explicit liking4 hours during each study interventionA visual analog scale ranging from 0 to 100 mm was utilized to evaluate the question, How pleasant would it be to taste some of this food now? with 0 indicating not at all and 100 signifying extremely.
Energy intake3 days during each study interventionParticipants are required to record their diet for the day before, the current day, and the day following the experiment.
Change in insulin4 hours during each study interventioninsulin in mU/L
Explicit wanting4 hours during each study interventionA visual analog scale ranging from 0 to 100 mm was utilized to evaluate the question, How much do you want some of this food now? with 0 indicating not at all and 100 signifying extremely.
Implicit wanting4 hours during each study interventionParticipants were given a set of food image pairs and were asked to select their preference by answering the question, Which food do you desire the most at the moment?. The implicit wanting calculation involved further consideration of response time data based on preference choices using a standardized equation.
Relative preference4 hours during each study interventionParticipants were given a set of food image pairs and were asked to select their preference by answering the question, Which food do you desire the most at the moment?. The relative preference was the sum of the times each type of food was chosen, with a maximum value of 48 and a minimum value of 0.
Fat appeal bias4 hours during each study interventionFat preference (high or low) was calculated by subtracting the mean low-fat scores from the mean high-fat scores. Positive values suggest a preference for high-fat foods, while negative scores indicate a preference for low-fat or savory foods, and a score of 0 signifies an equal preference between fat content.
Taste appeal bias4 hours during each study interventionTaste preference (savoury or sweet) was calculated by subtracting the mean savory scores from the mean sweet scores. Positive values suggest a preference for sweet foods, while negative scores indicate a preference for savory foods, and a score of 0 signifies an equal preference between taste categories.
Change in glucose4 hours during each study interventionglucose in mg/dL

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026