COPD
Conditions
Keywords
chronic obstructive pulmonary disease, handgrip strength, small airway disease, airway resistance, correlation
Brief summary
The goal of this observational study is to investigate the correlation between handgrip strength and small airway disease among patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is: • Is handgrip strength correlated with small airway disease in COPD patients? Participants will perform handgrip strength test and impulse oscillometry (IOS).
Detailed description
This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and impulse oscillometry will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Small airway disease will be assessed using IOS.
Interventions
DIAGNOSTIC_TESTHandgrip strength
Handgrip strength will be measured by 3 efforts.
Sponsors
Thammasat University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* COPD patients aged 40 years or older * Confirmed diagnosis by spirometry (post-bronchodilator FEV1/FVC \<0.7) * Smoking history 10 pack-years or more
Exclusion criteria
* COPD exacerbation within 3 months * Inability to perform handgrip strength test or impulse oscillometry
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between handgrip strength and small airway disease in COPD patients | At day 1 of the study | This correlation will be reported as correlation coefficient (R). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The best cutoff value of handgrip strength for predicting small airway disease in COPD patients | At day1 of the study | The best cutoff value will be determined by the area under the Receiver Operator Characteristic curve (ROC). |
Countries
Thailand
Outcome results
None listed