Biliary Tract Cancer, Portal Vein Embolization
Conditions
Brief summary
Portal vein embolization is often recommended to reduce the risk of postoperative liver failure and mortality. In this retrospective cohort study, researchers investigated the effect of portal vein embolization in patients with resectable perihilar cholangiocarcinoma bismuth type III and IV.
Interventions
PROCEDUREPotal vein embilization
Portal vein of involved bile duct is embolized to increase the volume of remnant liver.
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. patients with Bismuth type III or IV stricture on radiological examination, including computed tomography (CT) or magnetic resonance cholangiography 2. patients with perihilar cholangiocarcinoma histologically confirmed by surgical resection or forceps biopsy/brush cytology under endoscopic retrograde cholangiopancreatography or through the percutaneous transhepatic biliary drainage tract.
Exclusion criteria
1. patients with unresectable perihilar cholangiocarcinoma 2. patients who refused treatment 3. patients with other concomitant malignancies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival | The time from diagnosis until the date of death or last date of follow-up or end of study up to 24 months | Overall survival of each group (A-C). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence free survival | The time from surgical resection until the date of recurrence or death or last date of follow-up or end of study up to 24 months | Recurrence free survival of patients who underwent surgical resection |
Countries
South Korea
Outcome results
None listed