Chronic Kidney Diseases, Left Ventricular Systolic Dysfunction
Conditions
Keywords
first phase ejection fraction;left ventricular systolic dysfunction;echocardiography;chronic kidney disease
Brief summary
The goal of this observational study is to learn about the value of multimodal ultrasound in early detection of left ventricular systolic dysfunction in patients with chronic kidney disease(CKD). The main questions it aims to answer are: 1. If first-phase ejection fraction（EF1）could early detect the left ventricular systolic dysfunction in patients with CKD. 2. Whether EF1 can detect left ventricular systolic dysfunction in patients with CKD more sensitively than speckle-tracking echocardiography and myocardial work. Participants will need to cooperate to do an echocardiography. Researchers will compare healthy volunteers and patients with CKD to see if EF1 could early detect the left ventricular systolic dysfunction.
Interventions
None listed
Sponsors
Fifth Affiliated Hospital, Sun Yat-Sen University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with chronic kidney disease who are hospitalized in The Fifth Affiliated Hospital of Sun Yat-sen University. * LVEF≥50%.
Exclusion criteria
* Patients with primary hypertension, diabetes and congenital heart disease. * Patients who are pregnant or lactating. * Patients with the blurry ultrasound images.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| first-phase ejection fraction | 1 hour | an ultrasound indicator used to assess early left ventricular systolic function |
Countries
China
Outcome results
None listed