Comparison of Laparoscopic and Open Surgery for Colorectal Malignancy in Obese Patients

Analysis of the Prognostic Impact of Laparoscopic Surgery in Patients With Systemic Obesity and Colorectal Malignant Tumors

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06221878

Acronym

LOSCRO

Enrollment

473

Registered

2024-01-24

Start date

2009-01-31

Completion date

2022-12-31

Last updated

2024-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer, Obesity

Keywords

Colorectal cancer, obesity, laparoscopy surgery, open surgery, postoperative survival analysis

Brief summary

The goal of this observational study is to compare laparoscopic and open surgery outcomes in colorectal cancer patients with BMI ≥ 30 kg/m2 . The main question\[s\] it aims to answer are: 1. the short-term outcome and postoperative outcomes of patients treated with open group versus laparoscopy group 2. the long-term oncologic outcome of patients treated with open group versus laparoscopy group This study is a retrospective and observational study. Subjects were not be given or offered any treatment during the study. The investigator reviewed the patient's medical history and examination report to determine eligibility based on inclusion and exclusion criteria. If there is a comparison group: Researchers compared the open group and laparoscopy group to see if the laparoscopic group have better short-term outcomes with comparable oncologic outcomes to the open group.

Detailed description

This study is a retrospective and observational study. Subjects were not be given or offered any treatment during the study. The investigator reviewed the patient's medical history and examination report to determine eligibility based on inclusion and exclusion criteria. Given the uncertainty regarding the long-term outcomes of laparoscopy in obese patients with CRC, this study aimed to analyse a decade of data comparing laparoscopic and open surgery outcomes in patients with BMI ≥ 30 kg/m2 who had undergone treatment for CRC at the Linkou Chang Gung Hospital.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* CRC patients with BMI ≥ 30 kg/m2 who underwent colorectal surgery at the Linkou branch of the Chang Gung Memorial Hospital (CGMH) between January 2009 and December 2019.

Exclusion criteria

* non-adenocarcinoma neoplasms * Stage IV CRC

Design outcomes

Primary

Measure	Time frame	Description
Short-term outcome	2009 to 2019	Postoperative mortality risk

Secondary

Measure	Time frame	Description
Long-term Oncologic outcome	2009 to 2019	Disease-free survival (DFS)

Outcome results