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Study of Clinical Types and Treatment Outcomes of Pediatric Esotropia in Sohag University Hospital

Study of Clinical Types and Treatment Outcomes of Pediatric Esotropia in Sohag University Hospital

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06221098
Enrollment
40
Registered
2024-01-24
Start date
2022-04-01
Completion date
2023-10-01
Last updated
2024-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infantile Esotropia

Brief summary

Strabismus (or squint) is defined as the presence of misalignment between the visual axes of the 2 eyes presenting with deviation of the eyes. Strabismus is further subdivided into comitant (if the amount of misalignment between the 2 eyes remained equal in all directions of gaze) and incomitant (if the amount of misalignment varied in different directions of gaze). If the squinting eye was deviated inward, it is termed as a convergent squint or esotropia and if the squinting eye is deviated outward, it is termed as a divergent squint or exotropia. Pediatric esotropia may be congenital or acquired. Congenital esotropia is a well-defined entity with an onset prior to 6 months of age, characterised by a large stable angle, cross fixation, and a limited potential for binocular single vision. Acquired childhood esotropia may be paralytic or non-paralytic. The non-paralytic or concomitant type, which is neither congenital nor secondary to ocular pathology, can be divided into three main groups: (1) Accommodative esotropia, which may be fully accommodative, partially accommodative, or accommodative with convergence excess; (2) Non-accommodative esotropia; (3) Esotropia associated with neurological dysfunction, in particular cerebral palsy and hydrocephalus. The last group of esotropia will be excluded from our study. Pediatric strabismus must be treated early to maximize the potential for binocular vision and decrease the risk of amblyopia. Treatment goals include good vision in each eye (no amblyopia) and straight eyes (orthotropia). Both conditions are necessary to produce stereopsis, which is a third goal. Strabismus in children may result in undesirable appearance, amblyopia, impaired stereopsis, diplopia, and negative psychological effect.

Interventions

release muuscle from its original insertion and backword inserted in sclera

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
1 Days to 12 Years
Healthy volunteers
Yes

Inclusion criteria

1. Infants and children up to the age of 12 years. 2. Primary Concomitant convergent squint (1ry concomitant esotropia) 3. Candidate for surgical correction of squint

Exclusion criteria

* 1\. Children with: 1. Paralytic squint 2. Consecutive esotropia 3. Any neurological disorders e.g. hydrocephalus. 4. History of previous squint surgery 5. History of previous other ocular surgery (e.g. congenital cataract & glaucoma) 2. Children who missed follow up.

Design outcomes

Primary

MeasureTime frameDescription
orthotropia6 monthseye alignment
residual esotropia6monthsesotropia \>10PD undercorrection
consecuative exotropia6 monthsexotropia \> 10PD overcorrection

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026