Chronic Obstructive Pulmonary Disease
Conditions
Keywords
chronic obstructive pulmonary disease, handgrip strength, air trapping, lung volume, correlation
Brief summary
The goal of this observational study is to investigate the relationship between handgrip strength and air trapping in patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is: • Is handgrip strength correlated with air trapping in COPD patients? Participants will perform handgrip strength test and lung volume measurement.
Detailed description
This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and lung volume measurement will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Lung volume will be assessed using a body plethysmograph.
Interventions
DIAGNOSTIC_TESTHandgrip strength
Handgrip strength will be measured by 3 efforts.
Sponsors
Thammasat University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 40 years or older * Postbronchodilator FEV1/FVC \<0.7 * \>10 pack-year smoking history
Exclusion criteria
* COPD exacerbation within 3 months * Inability to perform handgrip strength test or lung volume measurement
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between handgrip strength and air trapping in COPD patients | At day 1 of the study | This correlation will be reported as correlation coefficient (R). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The best cutoff value of handgrip strength for predicting air trapping in COPD patients | At day 1 of the study | The best cutoff value will be determined by the area under the Receiver Operator Characteristic curve (ROC). |
Countries
Thailand
Outcome results
None listed