Gut Damage, Sport Performance
Conditions
Keywords
Probiotic, Gut damage, Sport performance, Females
Brief summary
This study will be performed with the aim to evaluate the effects of probiotic supplementation on sport performance and gut damage. Participants will be divided into two groups, placebo and experimental group. With the purpose to assess the effects of probiotics on the gut damage, a strenuous exercise session will be performed, and then blood samples will be taken to observe the variation of the selected intestinal damage marker. 24 hours after this strenuous session, performance tests will be performed. After the 4 weeks of supplementation, the same procedure will be followed to evaluate the effect of probiotics.
Detailed description
One week before the initiation of the study participants will be required to avoid consuming drugs, alcohol, cigarettes, probiotics, and any other food or liquid which could modify gut microbiota composition. For the baseline values, height, weight and sports performance test, of the participants will be collected. The same day, a strenuous exercise session will be performed in order to observe the variation of the intestinal damage marker (blood sample extraction just after finishing the strenous exercise session). 24 hours after that session sport performance tests will be conducted. Participants will then be randomly divided into two groups, one of which will take one probiotic capsule per day containing 10 billion colony-forming units (CFU) of Lactobacillus plantarum, and the other group will take one placebo capsule per day consisting of dextrose. The supplementation period will last 4 weeks. After the supplementation period, the same process will be followed, with the same strenuous exercise session and immediate blood sampling to determine the effects of probiotics on the intestinal damage caused by exercise. 24 hours later, performance tests will be conducted to assess the effects of probiotics on sport performance.
Interventions
DIETARY_SUPPLEMENTProbiotic
Probiotic capsules will be composed of 10 billion CFU of Lactobacillus plantarum.
DIETARY_SUPPLEMENTPlacebo
Capsules containing dextrose (1 capsule per day)
Sponsors
University of the Basque Country (UPV/EHU)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy * No injuries * 1 year of CrossFit practicing experience
Exclusion criteria
* Drug, alcohol, cigarettes, probiotic intake * Injuries
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intestinal-fatty acid-binding protein | 0-10 minutes after strenuous exercise blood samples will be extracted | Gut damage marker |
| Counter movement jump test | 24 hours after strenuous training session. First test to be performed | Jumping test |
| Running Based Anaerobic Sprint Test | 24 hours after strenuous training session. Second test to be performed | Running test |
| YO YO Intermittent Recovery Level test 1 | 24 hours after strenuous training session. Third test to be performed | aerobic test |
Countries
Spain
Outcome results
None listed