Allograft
Conditions
Keywords
Fascia lata allograft
Brief summary
To compare between the efficacy of fascia lata allograft and platelet rich fibrin versus subepithelial connective tissue graft on periodontal phenotype (thickness and width of keratinized tissue, labial bone thickness) around dental implant in upper anterior region.
Detailed description
In order to evaluate the effectiveness of fascia lata allograft, platelet-rich fibrin, and subepithelial connective tissue graft on periodontal phenotype (including the thickness and width of keratinized tissue, as well as the thickness of labial bone) around dental implants in the upper anterior region, the purpose of this study is to compare the three types of grafts.
Interventions
DRUGFascia lata membrane
novel allogenic derived acellular matrix produced from human fascia lata allograft
DRUGPlatlet Rich fibrin membrane
Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRF where autologous platelets and leukocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue
The connective tissue is generally taken from the hard palate, although it may be taken from other sites as well, such as the maxillary tuberosity area.
Sponsors
Kafrelsheikh University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Patients were classified into three main groups: Group 1 (Study group) It includes eight patients seeking for implant placement in the upper anterior areas and implants will be placed with the application of fascia lata allograft membrane. Group 2 (Study group) It includes eight patients seeking for implant placement in the upper anterior area and implants will be placed with the application of PRF. Group 3 (Control group) It includes eight patients seeking for single implant placement at the upper anterior area and those patients will be received their implants with subepithelial connective tissue graft.
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
1. Patients with thin gingival biotype (gingival thickness was ≤1 mm) 2. The height of keratinized gingiva for the site selected should be ≥2 mm. 3. Ability to maintain good oral hygiene as evidenced in recall visits.
Exclusion criteria
1. Smoker patient and pregnant or lactating woman. 2. Patient with poor oral hygiene or active periodontal disease. 3. Traumatic occlusion or para-functional habits such as clenching or bruxism. 4. Patient with limited mouth opening
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pink aesthetic score | 6 Months | Pink esthetic score The gingival response to a anterior esthetic evaluation is assessed by the Pink Esthetic Score (PES) from clinical photography |
Contacts
Primary ContactAhmed Elhadidy, Msc
Outcome results
None listed