Capsule Endoscopy in Iron Deficiency Anaemia

Diagnostic Yield of Video Capsule Endoscopy for Iron Deficiency Anaemia

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06219395

Acronym

WCE-IDA

Enrollment

100

Registered

2024-01-23

Start date

2024-03-01

Completion date

2025-09-30

Last updated

2024-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel Cancer, Iron Deficiency Anemia

Brief summary

This project aim to investigate whether wireless capsule endoscopy(WCE) has a similar diagnostic yield as conventional endoscopy in detecting the cause of iron deficiency anemia (IDA)

Detailed description

IDA is common and 90-95% of cases are caused by bleeding from ulcers, tumours or vascular malformations in the oesophagus, stomach, duodenum, small intestine or the large bowel.Bleeding from more than one localisation is common. International guidelines recommend bidirectional endoscopy(gastro- and colonoscopy) to detect and treat the source of bleeding. Our hypothesis is that WCE is non-inferior to the combination of gastroscopy and colonoscopy in locating GI-bleeding and that complete examinations will be achieved in ≥90% of the examinations.

Interventions

PROCEDUREEndoscopy

Patients will be examined with gastroscopy, colonoscopy and WCE and the diagnostic yield of combined gastroscopy/colonoscopy will be compared to WCE

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Inclusion criteria

* Referred to flexible endoscopy for a verified Iron Deficiency Anaemia

Exclusion criteria

* Unwillingness to participate * Not able to provide informed consent * Not understanding the instructions * Severe cardio-vascular disease New York Heart Association III-IV * Symptoms of bowel obstruction/previous bowel obstruction * Bowel surgery except for end to end anastomosis in the colon * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic yield	90 minutes	Mucosal lesions detected

Secondary

Measure	Time frame	Description
Adequate examinations	90 minutes	Proportion of adequate examinations defined as both satisfactory bowel preparation and complete examination
Small bowel lesions	90 minutes	Number of lesions detected in the small bowel
Complete examination	90 minutes	Proportion of complete examinations
Bowel preparation	90 minute	Proportion of satisfactory bowel preparation

Countries

Sweden

Contacts

Primary ContactThomas de Lange, PhD

thomas.de.lange@vgregion.se+46702794054

Backup ContactNikolaos Papachrysos, PhD

nikolaos.papachrysos@vgregion.se

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026