The Impact of Preoperative Anemia on Postoperative Anemia and Related Nutrient Abnormalities After Bariatric Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06218953

Enrollment

400

Registered

2024-01-23

Start date

2017-09-01

Completion date

2024-12-31

Last updated

2025-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia, Bariatric Surgery

Brief summary

This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities 1 year after bariatric surgery.

Detailed description

This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities (ferritin deficiency, vitamin B12 deficiency, folate deficiency, and low transferrin saturation level) at 1 year after bariatric surgery.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

16 Years to 70 Years

Inclusion criteria

* Patients who underwent bariatric surgery (sleeve gastrectomy and Roux-en-Y gastric bypass) * Age between 16 and 70 years * Patients who have complete 1-year follow-up data

Exclusion criteria

* Baseline renal failure * Vegetarian * Postoperative bleeding (it was defined as a drop in hemoglobin levels \> 3 g/dL or a confirmed blood loss requiring treatment after surgery)

Design outcomes

Primary

Measure	Time frame	Description
Odds ratio (OR) for anemia by preoperative anemia status	1 year	Multivariable logistic regression will be performed to assess the association between preoperative anemia and postoperative anemia. Several factors will be adjusted: sex, age, BMI, waist circumference, hip circumference, surgery, smoking, alcohol, hypertension, diabetes, hyperuricemia, hypercholesterolemia, and hypertriglyceridemia.

Secondary

Measure	Time frame	Description
Percentage of anemia severity	1 year	Percentage of anemia severity (mild: hemoglobin≥110g/L; moderate: hemoglobin≥80g/L; severe: hemoglobin\<80g/L).
Percentage of ferritin deficiency	1 year	Percentage of ferritin deficiency, which is defined as ferritin less than 30 ng/mL.
Percentage of postoperative anemia	1 year	Percentage of postoperative anemia,, , and low transferrin saturation level.
Percentage of folate deficiency	1 year	Percentage of folate deficiency, which is defined as folate less than 10 nmol/L.
Percentage of low transferrin saturation level	1 year	Percentage of low transferrin saturation level, which is defined as transferrin saturation less than 20%.
Percentage of vitamin B12 deficiency	1 year	Percentage of ferritin deficiency, which is defined as vitamin B12 less than 150 pmol/L.

Countries

China

Outcome results