Inguinal Hernia
Conditions
Keywords
hydromorphone, Quadratus lumbois block, old people
Brief summary
To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.
Detailed description
Elderly patients selected for Lichtenstein hernia repair in our hospital who met the inclusion and exclusion criteria and obtained informed consent were included in this trial, and were randomly divided into experimental group by random number table method: 0.375% ropivacaine combined with hydromorphone block group, and control group: 0.375% ropivacaine block group alone.
Interventions
DRUGHydromorphone combined with ropivacaine
1mg hydromorphone was added to 0.375% ropivacaine for a total of 30ml to perform quadrat block
DRUGRopivacaine
A mixture of 0.375% ropivacaine for a total of 30ml was used for quadrate block
Sponsors
Second Hospital of Jilin University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 60 and above. * Admission to hospital for open inguinal hernia surgery is consistent with the -indications of this surgical modality, ASA grades 1 to 3. * No recent use of sedatives, opioids, or other analgesics. * Good compliance, signed informed consent. * Complete clinical data.
Exclusion criteria
* There are serious cardiovascular and cerebrovascular diseases. * Abdominal infection. * Coagulation dysfunction or receiving anticoagulation therapy. * Local anesthesia drug allergy. * Can not cooperate with the corresponding operation, suffering from mental illness. * Previous surgical history of the corresponding position in the abdomen that may interfere with the surgical process of this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Related indexes of anesthesia effect: pain after surgery, 6, 12, 18,24, 48h after surgery. | From the end of surgery until two days after surgery. | Visual analogue scale (VAS) was used to score the postoperative pain at 6,12,18,24,48h.The score ranges from 0 (no pain) to 10 (most severe pain). The change was equal to the score difference between the two groups at different observation time points (6,12,18,24,48h). |
| Related indexes of anesthesia effect: time of onset of anesthesia, duration of anesthesia maintenance. | From the start of anesthesia until two days after surgery. | The range of the effective time of anesthesia minus the start time of anesthesia and the maintenance time minus the start time of anesthesia are respectively.The unit of time is minutes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The occurrence of postoperative adverse reactions. | The operation ended two days after surgery. | The rates of postoperative nausea, vomiting and dizziness were compared between the two groups. |
Countries
China
Outcome results
None listed