Chlamydia Trachomatis, Neisseria Gonorrhoeae, Uncomplicated Infections
Conditions
Brief summary
The aim of this study is to evaluate the negativation time of chlamydial and gonococcal PCRs after treatment for urogenital, oropharyngeal and anal infections.
Interventions
DIAGNOSTIC_TESTChlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) NAAT(s)
Test every week after the start of treatment, until NAAT negativation and up to a maximum of 4 weeks
Sponsors
University Hospital, Strasbourg, France
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \- Patients attending the Trait d'Union department at the Nouvel Hôpital Civil for PrEP consultations, AES or HIV infection. * Over 18 years of age * Male or female * Who have had an uncomplicated CT and/or NG infection treated with currently recommended therapies (Ceftriaxone 500mg DU for NG infections, Doxycycline 200mg per day for 1 week for rectal CT infections and Azithromycin 1g DU or Doxycycline 7 days for other CT infections). * Subject affiliated to a social health insurance scheme * Subject able to understand the aims and risks of the research and to give dated and signed informed consent
Exclusion criteria
* \- Complicated CT and/or NG infections: epididymitis, prostatitis, upper genital infection, extra-genital involvement (keratoconjunctivitis, arthritis, skin involvement, Fiessinger-Leroy-reiter syndrome, Fitz-Hugh-Curtis syndrome). * Interfering treatments and associated diseases: Severe immunosuppression (HIV infection with CD4 less than 200/mm3, chemotherapy in the last 6 months, active haemopathy, congenital immune deficiency, immunosuppressive treatment including corticosteroid therapy for more than 4 weeks or organ transplant. * Impossibility of giving the subject informed information (subject in an emergency situation, difficulties in understanding the subject, etc.). * Subject under court protection * Subject under guardianship or curatorship
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimate the rate of negativation of NAATs performed at the various sites of CT infection | 4 weeks after initiation of treatment |
Countries
France
Outcome results
None listed