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Recovery of TIVA vs Inhalation in Pediatric Anesthesia

Comparison of Emergence and Recovery Profile After Total Intravenous Anesthesia ( TIVA ) Vs Inhalational Anesthesia in Opioid Free Pediatric Tonsillectomy

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06215833
Enrollment
120
Registered
2024-01-22
Start date
2024-01-30
Completion date
2025-12-30
Last updated
2024-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Best Technique for Pediatric Anesthesia

Brief summary

Compare recovery profile from TIVA and that of total inhalational anesthesia in ambulatory pediatric tonsillectomy and which strategy is more safe and less cost and more smooth in pediatric anesthesia.

Detailed description

Complications in pediatric anesthesia can happen even in our modern hospitals with the most advanced equipment and skilled anesthesiologists. Typical complications in pediatric anesthesia are respiratory problems , medication errors , difficulties with intravenous puncture , and pulmonal aspiration. In postoperative setting , nausea and vomiting , pain , emergence delirium can be mentioned as typical complications. The choice of anesthetic agent and techniques can influence the occurrence of these complications and thus delay in discharge.

Interventions

DRUGPropofol

All children will undergo anesthesia via Propofol bolus injection in induction then Propofol infusion in maintenance of anesthesia and will be given after total recovery, Cetal suppositories as postoperative analgesia

DRUGSevoflurane

All children will undergo anesthesia via Sevoflurane will be given during induction then through maintenance of anesthesia and will be given after total recovery, Cetal suppositories as post operative analgesia

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
4 Years to 10 Years
Healthy volunteers
No

Inclusion criteria

* child between 4 to 10 years * without co morbidity * ASA score 1 * mallampati score 1 and 2

Exclusion criteria

* child below 4 years and above 10 years * child with co morbidity * ASA score above 1 * mallampati score 3 and 4

Design outcomes

Primary

MeasureTime frameDescription
level of consciousness scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* Awake =2 * Arousal with minimal stimulation =1 * Responsive only to tactile stimulation =0 * No score 0 is required & High score mean more safe and better method of anesthesia .
physical activity scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* Able to move on command =2 * Some weakness in movement = 1 * Unable to voluntarily move = 0 * No score 0 is required & High score mean more safe and better method of anesthesia .
hemodynamic stability scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* Blood pressure \< 15% of baseline MAP value =2 * Blood pressure 15%-30% of baseline MAP value =1 * Blood pressure \< 30% below baseline MAP value =0 * No score 0 is required & High score mean more safe and better method of anesthesia .
respiratory stability scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* Able to breathe deeply = 2 * Tachypnea with good coughs =1 * Dyspneic with weak cough = 0 * No score 0 is required & High score mean more safe and better method of anesthesia .
Oxygen saturation scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* Maintain value \> 90% on room air = 2 * Requires supplemental O2 to maintain value \> 90% = 1 * So2 \< 90% with supplemental O2 = 0 * No score 0 is required & High score mean more safe and better method of anesthesia .
post operative pain scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* None or mild = 2 * Moderate to severe pain controlled =1 * Persistent severe pain = 0 * No score 0 is required & High score mean more safe and better method of anesthesia .
post operative emetic scoreAbout 20 minutes after stopping anesthesia and emergence from anesthesia begin* None or mild nausea with no active vomiting = 2 * Transient vomiting =1 * Persistent moderate to severe nausea and vomiting=0 * No score 0 is required & High score mean more safe and better method of anesthesia .

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026