Astigmatism, Cataract
Conditions
Keywords
Astigmatism correction, Femtosecond laser arcuate keratotomy, Toric intraocular lens implantation, Femtosecond laser-assisted cataract surgery
Brief summary
In modern cataract surgery, residual astigmatism continues to be one of the major factors influencing patients' visual quality and satisfaction. The goal of this study is to compare the clinical outcomes of femtosecond laser arcuate keratotomy in one eye and Toric intraocular lens implantation in the contralateral eye for astigmatism correction in patients undergoing femtosecond laser-assisted cataract surgery. The study is a prospective randomized comparative study. Patients with binocular regular corneal astigmatism ranging from 0.75 to 3.00 D will be recruited. The patient will randomly receive femtosecond laser arcuate keratotomy in one eye and receive Toric intraocular lens implantation in the contralateral eye. Long term evaluation will be performed to compare the visual acuity, subjective manifest refraction, and corneal topography between groups.
Interventions
PROCEDUREFemtosecond laser arcuate keratotomy
The patient will receive femtosecond laser arcuate keratotomy and femtosecond laser-assisted cataract surgery with implantation of a monofocal intraocular lens in one eye.
PROCEDUREToric intraocular lens implantation
The patient will receive femtosecond laser-assisted cataract surgery with implantation of a Toric monofocal intraocular lens in the contralateral eye.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* cataract patients * patients with binocular regular corneal astigmatism ranging from 0.75 to 3.00 D * patients who plan to receive femtosecond laser-assisted cataract surgery
Exclusion criteria
* patients with ocular surface abnormalities such as irregular corneal astigmatism, corneal scarring, keratoconus, and pterygium) * patients with history of ocular trauma or surgery * patients with coexisting ocular disorders such as glaucoma, retinal vascular occlusive disease, retinal detachment, diabetic retinopathy, and any optic nerve-related pathologies * patients with concurrent severe systemic diseases * patients who lack of cooperation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Refractive astigmatism | 1 day, 1 week, 1 month, 3 months and 1year postoperatively | subjective manifest refraction and residual astigmatism |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual acuity | 1 day, 1 week, 1 month, 3 months and 1year postoperatively | uncorrected distance visual acuity and corrected distance visual acuity |
Other
| Measure | Time frame | Description |
|---|---|---|
| Keratometric astigmatism | 1 day, 1 week, 1 month, 3 months and 1year postoperatively | Corneal topography measurement |
Countries
China
Contacts
Primary ContactYueyang Zhong
Outcome results
None listed