IDH1 and OCT4 in High Grade Astrocytoma

IDH1 and OCT4 Markers as a Prognostic Factor in Clinical Outcome of High Grade Astrocytic Glioma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06214689

Enrollment

Registered

2024-01-19

Start date

2024-09-30

Completion date

2025-08-31

Last updated

2024-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Grade Astrocytoma

Brief summary

observation of IDH1 and OCT4 markers level and high grade astrocytoma patients prognosis after excision.

Detailed description

explore the relationship between prognosis and IDH1 and OCT4 biomarkers after high grade astrocytoma excision , according to progression free survival and overall survival , in prospective and retrospective samples.

Interventions

OTHERbiomarkers analysis

IDH1 and OCT4 markers analysis of surgical specimens of high grade astrocytoma

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients of high grade astrocytic glioma patients fit for surgery

Exclusion criteria

* patients of low grade glioma patients unfit for surgery

Design outcomes

Primary

Measure	Time frame	Description
IDH1 and OCT4 markers and their relation to postoperative prognosis of high grade astrocytoma patients	baseline	explore the relationship between prognosis (progression free and overall survival ) and biomarkers (IDH1 and OCT4 ) after excision of high grade astrocytoma

Countries

Egypt

Contacts

Primary ContactAbdelrahman A Salama, resident

adhamsalama001@gmail.com01002796190

Backup ContactMahmoud H Ragab, professor

Ragabm@gmail.com01004001789

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026