Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray

Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray Pre Endotracheal Intubation in Adult Undergoing General Anesthesia.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06213116

Enrollment

125

Registered

2024-01-19

Start date

2021-12-01

Completion date

2023-07-01

Last updated

2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough, Hemodynamic Instability, Hoarseness, Sore Throat

Keywords

lignocaine, MADgic Atomizer, airway anesthesia

Brief summary

Comparing the efficacy between Lignocaine given via MADgic Atomizer and Lignocaine Pump Spray pre endotracheal intubation in adult undergoing General Anesthesia.

Detailed description

Comparing the efficacy of Lignocaine given via 2 device (Lignocaine Spray and MADGIC Atomizer) on hemodinamic parameters postintubations and severity grading of post operative sore throat, cough and hoarseness of voice.

Interventions

DEVICEMADgic Atomizer

Device to deliver directly lignocaine

DEVICELignocaine pump spray

Lignocaine 30 mg (3 puffs) given via 10mg Lignocaine Pump Spray prior to endotracheal intubation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Masking description

Participant and Outcome Assessor do not know type of intervention

Intervention model description

Prospective, randomized control study.

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Adult with the age of 18 to 65 years old * Gender of both male and female * Planned for elective surgery scheduled at General Operation Theatre that require elective intubation for general anesthesia * American Society Anaesthesiologist (ASA) preoperative physical status assessment of 1 and 2 * Airway assessment Malampati scoring 1and 2.

Exclusion criteria

* Pregnancy * Known allergy or hypersensitivity to Lignocaine * Pre existing sore throat or hoarseness of voice identified during preoperative assessment. * The use of airway device other than endotracheal tube (ETT) such Laryngeal Mask airway/Supraglottic Device' * Oral and neck surgery

Design outcomes

Primary

Measure	Time frame	Description
Severity Grading of Post Operative Sore Throat	24 hours	Numbers of participants complaining incidence of sore throat postoperatively

Secondary

Measure	Time frame	Description
Severity Grading of Post Operative Cough	24 hours	Numbers of participants complaining incidence of cough postoperatively
Severity grading of Hoarseness of voice	24 hours	Numbers of participants complaining incidence of hoarseness of voice postoperatively

Countries

Malaysia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026