Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
Conditions
Brief summary
Project RESET is a Singapore National Medical Research Council Large Collaborative Grant funded program that brings together a nationwide community of cardiovascular, metabolic, and digital health researchers, as well as clinicians across primary and tertiary care to study the immune, lipid and metabolic drivers of early cardiovascular disease. RESET incorporates a nested randomised controlled trials (RCT) to test the use of a combined digital wearable and AI-human symbiotic lifestyle intervention to halt or reverse the progression of early disease.
Interventions
BEHAVIORALDigital wearable and AI-human symbiotic lifestyle intervention
Digital wearable and AI-human symbiotic lifestyle intervention
Sponsors
National University of Singapore
National University Hospital, Singapore
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Inclusion criteria
* 40-70 years old * ASCVD (atherosclerotic cardiovascular disease) score of 5% and higher
Exclusion criteria
* Previous major cardiovascular disease (myocardial infarction, heart failure, ischemic stroke) * Limited life expectancy * Other ongoing unstable medical conditions * Pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major adverse cardiovascular event | 5 years | Composite of cardiac death, non-fatal myocardial infarction, resuscitated cardiac arrest, non-fatal ischemic stroke, congestive heart failure, coronary revascularization |
Countries
Singapore
Contacts
Primary ContactHayang Yang, PhD
Outcome results
None listed