Elective Fertility Preservation
Conditions
Keywords
Endometriosis, Adenomyosis, Prevalence, Elective fertility preservation, Transvaginal pelvic ultrasound
Brief summary
Our study aims to assess the prevalence of adenomyosis and endometriosis in patients consulting for elective fertility preservation through the diagnosis of these pathologies by transvaginal pelvic ultrasound. Imaging data will be compared with clinical data (patient characteristics, clinical symptoms) as well as the assessment of anxiety, depression, and quality of life collected from the women.
Detailed description
Adenomyosis and endometriosis are two heterogeneous benign gynecological pathologies, in terms of the presence of diverse phenotypes and their symptomatic presentation: While some women are entirely asymptomatic, others experience pelvic pain, infertility, or abnormal uterine bleeding. Assessing the prevalence of these two pathologies is challenging: On the one hand, a significant number of women are asymptomatic and not considered in the calculation; on the other hand, endometriosis and adenomyosis are often underdiagnosed, leading to delayed diagnosis. Endometriosis and adenomyosis are frequently associated. Improving knowledge about the epidemiology of endometriosis and adenomyosis is crucial as both are major causes of clinical symptoms that adversely affect the quality of life in numerous women. This is a significant issue for women's health due to the associated suffering, numerous surgical interventions, healthcare expenses, and the suggested link with pathologies that may affect other organs. Understanding the disease could lead to improved treatment and the development of preventive strategies. Therefore, it is urgent to determine the frequency of endometriosis and adenomyosis, as well as the correlation between women's characteristics, especially their clinical symptoms, and different phenotypes. In order to assess the prevalence of adenomyosis and endometriosis in a population of women of reproductive age, the investigators intend to conduct this single-center study focusing on patients consulting for non-medical fertility preservation.
Interventions
OTHERUsual follow-up
Usual follow-up
Sponsors
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
29 Years to 37 Years
Healthy volunteers
No
Inclusion criteria
* Woman aged between 29 and 37 * Consultant for non-medical fertility preservation in the Reproductive Medicine Unit Port Royal, Cochin * Informed and not opposed to this research * Affiliated to a social security scheme
Exclusion criteria
* Pregnant women * Refusing to take part in the study * Under court protection, curatorship or guardianship * Women with a known malformation of the genital tract
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Transvaginal pelvic ultrasound | Up to month 6 | Search for endometriosis and adenomyosis on transvaginal pelvic ultrasound and characterisation of lesions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Self-questionnaire | Inclusion | Socio-demographic data |
| Quality of life assessment (WHO-QOL-BREF) | Inclusion | Between 26 (Poor quality of life) and 130 (good quality of life) |
| Hospital Anxiety and Depression Scale (HADS) | Inclusion | 2 scores between 0 (No anxiety or depression) and 21 (lots of anxiety and depression) |
Countries
France
Contacts
CONTACTMathilde BOURDON, MD
CONTACTMarie Benhammani-Godard
Outcome results
None listed