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Drugs Experience for Adolescents With Anorexia

Subjective Experience of Psychotropic Drugs Among Adolescents (Their Parents and Professionals) With Anorexia Nervosa

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06211517
Acronym
E3P
Enrollment
90
Registered
2024-01-18
Start date
2024-05-20
Completion date
2027-12-31
Last updated
2025-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent, Anorexia Nervosa, Psychotropic Drugs

Keywords

Adolescents, Anorexia nervosa, Psychotropic drugs, Qualitative research, Thematic analysis

Brief summary

The purpose of this study is to access to the experiences of adolescents, their parents and healthcare professionals regarding psychotropic drugs in anorexia nervosa. No preconceived ideas (according to qualitative methods) but a question: what are the participants' perceptions and experiences of psychotropic drugs in anorexia nervosa? In an adolescent medicine department.

Detailed description

Psychotropic prescription is common to adolescents suffering from anorexia nervosa. A first qualitative study (E3A Protocol Experience of adolescents with anorexia nervosa toward antidepressants) looked at the experience of antidepressants among 15 adolescents suffering from anorexia nervosa. Analysis of the interviews identified two meta-themes: 1. Reactions to the proposal of antidepressant with an opposition phase (about the existence of depressive symptoms and about negative preconceptions) and need to share with family and other teenagers. 2. Reactions to antidepressant use with ambivalence and an initial perception of coercion, and effects of antidepressants (psychological effects, effects on the body and on anorexia nervosa and effects perceived through the eyes of others). Nine adolescents (out of 15) were also taking an atypical antipsychotic (APA) often prescribed in case of anorexia nervosa resistance. The need to share with family about the proposal of antidepressant and the effects perceived through the eyes of others (including parent's eyes) lead us to take an interest in parents perceptions. Two decisive periods were identified: What do healthcare professionals think about psychotropic treatments for anorexia nervosa in adolescence? How do they propose treatment? Interviewing teenagers, their parents as well as healthcare professionals, will enable to access to the complexity of representations and experiences of these psychotropic drugs in anorexia nervosa.

Interventions

OTHERSemi-structured interviews with visual mediations

Semi-structured interviews with visual mediations / An hour-long interview

OTHERSemi-structured interviews

Semi-structured interviews

Sponsors

URC-CIC Paris Descartes Necker Cochin
CollaboratorOTHER
Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Adolescents : * Aged 12 to 25 years * Suffering from anorexia nervosa (restrictive or mixed) according to DSM-5 (Diagnostic and Statistical Manual) criteria * Received psychotropic drugs (antidepressant treatment and/or APA) during their care, either ongoing or discontinued before this study started Parents of adolescents suffering from anorexia nervosa for whom a psychotropic drug has been prescribed and whose adolescents meet inclusion criteria Healthcare Professionals working with adolescents suffering from eating disorders

Exclusion criteria

Adolescents : * Atypical eating disorder that does not meet the DSM-5 criteria for restrictive or mixed anorexia nervosa * BMI\<15 * Prescription of an antidepressant other than an SSRI (Selective Serotonin Reuptake Inhibitor) * Prescription of an APA for the indication of psychotic symptoms

Design outcomes

Primary

MeasureTime frameDescription
Semi-structured interviewDay of inclusionThemes describing adolescent experiences regarding psychotropic drugs in anorexia nervosa - Emergence of themes describing participants' experience from analysis of qualitative interviews (with Interpretative Phenomenology Analysis methodology)

Secondary

MeasureTime frameDescription
Semi-structured interviewDay of inclusionThemes describing parents experiences regarding psychotropic drugs for their children suffering from anorexia nervosa - Emergence of themes describing participants' experience from analysis of qualitative interviews (with Interpretative Phenomenology Analysis methodology)

Countries

France

Contacts

Primary ContactMaude Ludot-Gregoire, MD, psychiatrist
maude.ludot@aphp.fr00 33 1 58 41 28 41
Backup ContactMarie Benhammani-Godard
marie.godard@aphp.fr00 33 1 58 41 11 90

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026