Skip to content

Artificial Intelligence for Screening of Multiple Corneal Diseases

Application of Deep Learning for Screening Multiple Corneal Diseases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06211218
Enrollment
3000
Registered
2024-01-18
Start date
2020-12-06
Completion date
2024-12-06
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Disease, Deep Learning, Screening

Brief summary

This study developed a deep learning algorithm based on anterior segment images and prospectively validated its ability to identify corneal diseases.The effectiveness and accuracy of this algorithm was evaluated by sensitivity, specificity, positive predictive value, negative predictive value, and area under curve.

Interventions

DIAGNOSTIC_TESTCornea diseases diagnosed by artificial intelligence algorithm

An artificial intelligence algorithm was applied to diagnose cornea diseases from slit-lamp images.

Sponsors

Tianjin Eye Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

1. The quality of slit-lamp images should clinical acceptable. 2. More than 90% of the slit-lamp image area including three main regions (sclera, pupil, and lens) are easy to read and discriminate.

Exclusion criteria

1)Insufficient information for diagnosis.

Design outcomes

Primary

MeasureTime frameDescription
Area under curve1 weekWe used the receiver operating characteristic (ROC) curve and area under curve to examine the ability of this artificial intelligence algorism recognition and classification of corneal diseases.
Sensitivity and specificity1 weekWe used sensitivity and specificity to examine the ability of this artificial intelligence algorism recognition and classification of corneal diseases.

Countries

China

Contacts

Primary ContactYan Huo, Master
hy13102118953@163.com13102118953

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026