Intensive Care Unit Acquired Weakness
Conditions
Brief summary
Intensive care unit-acquired weakness (ICU-acquired weakness) may be caused by a variety of different causes. Several studies have shown that ICU-acquired weakness occurs in up to 30% of critically ill patients. It affects daily activities, walking, and functional performance
Detailed description
Forty ICU-acquired weakness elderly patients will be randomly assigned to group A and group B, 20 elderly for each. Both groups will receive chest physiotherapy (cough training, vibration, percussion, rib springing, and postural drainage), 30 minutes of resisted training on upper- and lower-limb muscles (15 min on upper limb and 15 min on lower limb), and 30 minutes of neuromuscular electrical stimulation of lower- and upper-limb muscles (triceps and wrist extensors, dorsiflexors, and quadriceps). sessions will be executed 5 times weekly). Group A only will receive 3-set IMT (two sessions daily via threshold IMT, the set contain 10 repetitions) 5 times weekly. The study duration will be 1 month.
Interventions
BEHAVIORALThreshold IMT and traditional physical therapy program
twenty ICU-acquired weakness elderly patients will receive chest physiotherapy (cough training, vibration, percussion, rib springing, and postural drainage), 30 minutes of resisted training on upper- and lower-limb muscles (15 min on upper limb and 15 min on lower limb), and 30 minutes of neuromuscular electrical stimulation of lower- and upper-limb muscles (triceps and wrist extensors, dorsiflexors, and quadriceps). sessions will be executed 5 times weekly). this Group will receive 3-set IMT (two sessions daily via threshold IMT, the set contain 10 repetitions) 5 times weekly. The study duration will be 1 month.
BEHAVIORALtraditional physiotherapy program
twenty ICU-acquired weakness elderly patients will receive chest physiotherapy (cough training, vibration, percussion, rib springing, and postural drainage), 30 minutes of resisted training on upper- and lower-limb muscles (15 min on upper limb and 15 min on lower limb), and 30 minutes of neuromuscular electrical stimulation of lower- and upper-limb muscles (triceps and wrist extensors, dorsiflexors, and quadriceps). sessions will be executed 5 times weekly).
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* sufferers with intensive care unit acquired weakness * Older sufferers patients with severe walking disability detected by Modified Functional Ambulation Category test,
Exclusion criteria
* lower limb amputations * orthopedic or spinal disc disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Modified Functional Ambulation Category Test | it will be measured after 1 month | it is a category test used to assess walking disability |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Partial Pressure of carbon dioxide | It will be measured after 1 month | it is an arterial blood gas test |
| Oxygen saturation | It will be measured after 1 month | it is an arterial blood gas test |
| functional vital capacity | It will be measured after 1 month | the percentage of predicted value of functional vital capacity will be assessed |
| forced expiatory volume in the first second of expiration | It will be measured after 1 month | the percentage of predicted value of FEV1 will be assessed |
| inspiratory muscle strength | It will be measured after 1 month | it will be measure in cm H2O |
| expiratory muscle strength | It will be measured after 1 month | it will be measure in cm H2O |
| Partial Pressure of Oxygen | It will be measured after 1 month | it is an arterial blood gas test |
| 30-second sit to stand | It will be measured after 1 month | number of (sit to stand) done in 30 seconds |
| six-minute walk test, | It will be measured after 1 month | distance walked in 6 minute |
| 10-meter walking test | It will be measured after 1 month | it is time used to walk a 10-meter distance |
| mental division of short form 36 | It will be measured after 1 month | it assess mental component of short form 36 quality of life questionnare |
| physical division of short form 36 | It will be measured after 1 month | it assess physical component of short form 36 quality of life questionnare |
| time up and go test | It will be measured after 1 month | it is time used to walk a three-meter distance |
Countries
Egypt
Contacts
Primary ContactAli MA Ismail, lecturer
Backup Contacthany elsisi, professor
Outcome results
None listed