Metabolic Syndrome
Conditions
Keywords
metabolic syndrome, MLCT
Brief summary
Double-blind and placebo-controlled study on intervention effect of medium and long chain fatty acid triglyceride on glycolipid homeostasis in patients with metabolic syndrome and mechanisms
Interventions
DIETARY_SUPPLEMENTMLCT supplementation
MLCT 25g/d for 6 months
DIETARY_SUPPLEMENTOlive oil
Matching placebo (olive oil) 25g/d for 6 months
Sponsors
Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosed metabolic syndrome according to IDF diagnostic criteria; * Rarely eating out of home; * Aged between 40 and 70 years.
Exclusion criteria
* Breastfeeding or pregnancy; * History of heart disease, coronary heart disease, stroke, cerebral infarction, viral liver disease (hepatitis A, hepatitis B, etc.), chronic kidney disease (GFR\<60 ml/min) or cancer; * Diabetic ketoacidosis or hyperketosis; * Drug use has changed in the past six months; * Taking insulin; * Used MLCT edible oil in the past six months; * Have participated in other clinical trials in the last three months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in blood lipids from baseline | 6 months | The investigators will measure Triglycerides (TG), total cholesterol (TC), LDL-C, and HDL-C levels in blood samples before and after treatment. |
| Change in blood glucose from baseline | 6 months | The investigators will measure HbA1c and fasting plasma glucose levels in blood samples before and after treatment. |
Countries
China
Outcome results
None listed