Bone Resorption
Conditions
Brief summary
Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.
Detailed description
Chronic hyperglycemia is considered as a typical risk-factor that causes soft tissue inflammation and bone loss around natural teeth and implants. One possible explanation for this mechanism is that chronic hyperglycemia has the propensity to increase the levels of accumulated glycation end products (AGEs) in the serum and oral tissues that accelerates the production of proinflammatory cytokines that induce bone destruction around natural teeth and implants. However, it is relevant to indicate that dental implants in chronic hyperglycemia under ideal glycemic conditions can successfully osseointegrate and show predictable outcomes over long durations in both diabetic and non-diabetic patients. Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.
Interventions
OTHERObservational study
evaluate implant survival, peri-implant outcome of 4 implant retained mandibular OVD after 10 years of function.
Sponsors
Menoufia University
Mansoura University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
55 Years to 65 Years
Inclusion criteria
* Patients with edentulous maxilla and mandible for at least 12 months. * Patients have problems with mandibular denture retention and stability. * Patients with a mandibular bone height measured on a panoramic x-ray between 15 and 25 mm at the mandibular symphysis region.
Exclusion criteria
* Patients who did not receive implants at the department clinic. * Patients with more or less than 4 implants in the mandible. * Patients with well controlled diabetics. * Patients with relative contraindications, such as a history of parafunctional habits, daily smokers of more than 10 cigarettes, or alcoholism. * Patients who have previously received head and neck radiation therapy; furthermore, patients receiving intravenous bisphosphonates, chemotherapy, or psychological disorders could jeopardize their cooperation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Crestal bone loss around implants | This is a retrospective study, Measurement will be performed after implants being in service by 10 years | amount of bone loss which appears on a periapical radiograph |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth | This is a retrospective study, Measurement will be performed after implants being in service by 10 years | By using a plastic periodontal probe to measure the probing depth around the implants |
Countries
Egypt
Contacts
Primary ContactMohammed Elsawy, PhD
Backup ContactDoaa A. mewafy, PhD
Outcome results
None listed