Anesthesia, General, Pulmonary Atelectasis
Conditions
Brief summary
Atelectasis after induction of general anesthesia is common even in healthy patients and is clinically problematic, especially in obese patients. We aim to investigate whether preoxygenation with high-flow nasal oxygen during anesthesia induction reduces atelectasis in obese patients.
Interventions
preoxygenation using high-flow nasal oxygen, FiO2 1.0, 40 L/min, 3 min
OTHERfacemask
preoxygenation using facemask, FIO2 1.0, fresh gas flow 10 L/min, 3 min
Sponsors
SMG-SNU Boramae Medical Center
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults patients undergoinig surgery under general anesthesia with a BMI of 30 kg/m2 or greater who have given informed consent
Exclusion criteria
* surgery time less than 2 hours * Nasotracheal intubation * Severe cardiac or respiratory disease * History of difficult airway * History of a surgery or anatomical anomaly in the head and neck * History of Inability to breathe through nose * Gastric reflux disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lung ultrasound score | Immediately after anesthesia induction | modified LUSS |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| PaO2 to FiO2 ratio and PaCO2 | Immediately after anesthesia induction | — |
| Hemodynamic variables | During anesthesia induction | Blood pressure, heart rate, pulse oximetry |
| Patient Satisfaction Score | During preoxygenation | — |
| Lung ultrasound score | In the PACU after surgery | — |
| Incidence of atelectasis | Immediately after anesthesia induction | — |
| Maximum body temperature | during hospitalization up to 1 week | — |
| Incidence of postoperative pulmonary complications | during hospitalization up to 1 week | — |
| length of hospital stay | up to 1 year | — |
| Incidence of Spo2 less than 95% | during 48 hours postoperatively | — |
Countries
South Korea
Contacts
Primary ContactTAE KYONG KIM
Outcome results
None listed