Focused Ultrasound Thalamotomy for Tremor Relief in Atypical Parkinsonism

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06204575

Acronym

FUSAP

Enrollment

Registered

2024-01-12

Start date

2013-11-01

Completion date

2023-05-31

Last updated

2024-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atypical Parkinsonism, Dementia With Lewy Bodies, Multiple System Atrophy, MSA

Keywords

focused ultrasound, tremor, surgery, thalamotomy

Brief summary

The goal of this retrospective observational study is to describe the efficacy of focused ultrasound ventral-intermediate nucleus thalamotomy in patients with atypical parkinsonism. * Is this treatment efficacious in patients with multiple system atrophy? * Is this treatment efficacious in patients with diffuse Lewy Body Dementia? Data will be collected from patients charts.

Interventions

OTHERData collection

Data collection

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

Inclusion Patients that underwent FUS ventral-intermediate nucleus thalamotomy Suffer from multiple system atrophy-Parkinsonian type (MSA-P) or dementia with Lewy bodies (DLBD). \-

Exclusion criteria

* Patients that did not underwent FUS ventral-intermediate nucleus thalamotomy * Patients that underwent FUS ventral-intermediate nucleus thalamotomy and do not suffer from MSA or DLBD

Design outcomes

Primary

Measure	Time frame	Description
Clinical Rating Scale for Tremor	baseline, pre-procedure, 1 month, 6 months and 1 year following procedure	tremor assessment by Clinical Rating Scale for Tremor. Scores ranging from 0 to 156, with higher scores indicating more severe tremor.

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026