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Association Between Labor Induction and Birth Weight in Cases of Fetal Macrosomia: The MACROMODA Cohort Study

Association Between Labor Induction and Birth Weight in Cases of Fetal Macrosomia: The MACROMODA Cohort Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06198881
Acronym
MACROMODA
Enrollment
4500
Registered
2024-01-10
Start date
2023-10-01
Completion date
2024-01-01
Last updated
2024-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Birth Weight, Macrosomia, Fetal

Keywords

macrosomia, labor induction, perineal tears, hemorrhage, full-term deliveries, singleton

Brief summary

The rising prevalence fof fetal macrosomia represents a significant challenge in obstetrics, affecting both maternal and neonatal outcomes. Such challenges include complications like perineal tears and postpartum hemorrhage. Concurrently, the frequency of labor induction practices on the rise, yet the implications for neonatal weight are inadequately understood. To address this gap, our study aims to evaluate the association between labor induction and neontal birth weight through a population-based cohort study. The findings have the potential to inform more accurate clinical guidelines, thereby enhancing the quality of maternity care.

Interventions

None listed

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
12 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Full-term deliveries (≥ 37 weeks of gestation) * Singleton * Birth weight \> 4000g * Complete medical records available for analysis

Exclusion criteria

* Delivery \< 37 weeks * Uterus \> bi-scarred * Presentation of the headquarters * Maternal or fetal pathology modifying the route/time of delivery (pre-eclampsia, fetal heart rate abnormalities, cholestasis, chorioamnionitis, metrorrhagia, covering placenta, etc.)

Design outcomes

Primary

MeasureTime frameDescription
Number of vaginal deliveries among the population studiedduring DeliveryNumber of vaginal deliveries among the population studied

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 29, 2026