Dentine Hypersensitivity
Conditions
Keywords
Dentin Hypersensitivity, Toothpaste, Fluoride, Arginine, Nano-Hydroxyapatite
Brief summary
Dentin hypersensitivity is a common problem in society. Untreated hypersensitivity affects the patient's quality of life, complicates plaque control and increases the risk of caries and periodontal disease. This study aimed to evaluate the clinical efficacy of desensitizing toothpastes containing sodium fluoride, stannous fluoride, nano-hydroxyapatite, 8% arginine and calcium carbonate. Fourty eight patients with at least two teeth with positive responses to air and mechanical stimulus were included in the study and were divided into four groups. Sodium fluoride (Colgate®, Cavity Protection) in group A, stannous fluoride (Oral B® Gum Calm & Sensitivity) in group B, nano-hydroxyapatite (ApaCare®) in group C and 8% arginine and calcium carbonate combination in group D (Colgate® Sensitive Pro- ReliefTM) were used by the patients continuously for 16 weeks. Dentin hypersensitivity, by using VAS and Shiff scores and periodontal parameters were evaluated at baseline, 2nd week, 4th week and last 16th week.
Interventions
Test toothpaste, participants will brush selected sensitive teeth each for 30 seconds followed by the whole mouth thoroughly for at least one minute. The method of application of these agents will be the fingertip method. Patients continued to use the paste twice daily, morning and evening, for 16 weeks.
OTHERStannous Fluoride
Test toothpaste, participants will brush selected sensitive teeth each for 30 seconds followed by the whole mouth thoroughly for at least one minute. The method of application of these agents will be the fingertip method. Patients continued to use the paste twice daily, morning and evening, for 16 weeks.
OTHERNano-Hydroxyapatite
Test toothpaste, participants will brush selected sensitive teeth each for 30 seconds followed by the whole mouth thoroughly for at least one minute. The method of application of these agents will be the fingertip method. Patients continued to use the paste twice daily, morning and evening, for 16 weeks.
OTHER8% Arginine & Calcium Carbonate
Test toothpaste, participants will brush selected sensitive teeth each for 30 seconds followed by the whole mouth thoroughly for at least one minute. The method of application of these agents will be the fingertip method. Patients continued to use the paste twice daily, morning and evening, for 16 weeks.
Sponsors
Altinbas University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Dentin hypersensitivity complaints * Systemically healthy * Not during pregnancy & lactation * No sensitivity treatment in the last 6 months * Forty-eight patients with positive response to VAS and Schiff tests were included.
Exclusion criteria
People who have; * Any systemic disease * Take regular medication for any other reason * Undergone periodontal surgery within the last 6 months, * History of allergy to toothpaste materials, * Active caries, restoration and/or bridge on the sensitive tooth, * Orthodontic appliances,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypersensitivity Reduction | Baseline, 2nd week, 4th week, 16th week | Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be'). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Periodontal Measurements | Baseline, 16th week | Probing depths (mm) |
Countries
Turkey (Türkiye)
Outcome results
None listed