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Indoor Air Quality Monitoring and Impact on Children's Health

Development of Novel Assessments for Indoor Air Quality Monitoring and Impact on Children's Health - Cohorts in Schools & Biomarkers of Exposure

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06197477
Acronym
LEARN
Enrollment
900
Registered
2024-01-09
Start date
2023-11-20
Completion date
2025-12-31
Last updated
2024-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognition

Keywords

indoor air pollution, indoor air quality, cognition in children

Brief summary

This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe

Detailed description

The LEARN project, funded by the European Commission, aims to gain an in-depth understanding about indoor air quality in schools and its impact on children's cognitive development. This involves evaluating school cohorts in three different countries (Belgium, Greece and Denmark). In participating schools, we measure and characterise indoor and outdoor air pollutants and evaluate the presence of exposure biomarkers and their effect on children's cognition. Measuring indoor air quality, exposure and creating remedial strategies are crucial steps to improve air quality in the school environment and ensure the well-being of children.

Interventions

DEVICEOurAir SQ 1750 - Mobile Air Purification System for indoor

Filtration device will be placed in classrooms. Computational Fluid Dynamics simulations will be used to find optimal position and operation mode for air purification systems in classrooms.

DEVICESham intervention

Filtration will be turned off in the control part of the study and then will be turned on during the intervention.

Sponsors

Hasselt University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
9 Years to 12 Years
Healthy volunteers
No

Inclusion criteria

* Boys and girls * Attending school in the 4th -6th grade in elementary schools included in the study * Signed informed consent form by legal representative

Exclusion criteria

* Insufficient knowledge of local language (ie. Dutch, Greek, Danish) by child or parents

Design outcomes

Primary

MeasureTime frameDescription
Change in Correct Detection of continuous Performance Testat the end of the intervention and at the end of the sham interventionChange in the number of times the child responded correctly to the target alphanumeric stimulus. Higher rates of correct detections indicate better attentional capacity.
Change in the number of correct substitutions of Symbol Digit Modalities Testat the end of the intervention and at the end of the sham interventionChange in the the number of correct substitutions the child performed. Higher number of correct substitutions indicate better information processing ability.
Change in the Memory Span Task scoreat the end of the intervention and at the end of the sham interventionChange in the number of longest list of items that a child can repeat back in correct order. Longer list of recalled items indicate better short term memory
Change in the Signal Detection Test scoreat the end of the intervention and at the end of the sham interventionChange in the number of correct detection of signals. Higher rates of correct detection indicate better perception ability

Countries

Belgium

Contacts

Primary ContactRossella Alfano, PhD
rossella.alfano@uhasselt.be+3281739400
Backup ContactNawrot

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 4, 2026