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The Relationship of Shear Wave Elastography Findings With Pain Threshold and Quality of Life in Patients With Lipedema

The Relationship of Shear Wave Elastography Findings With Pain Threshold and Quality of Life in Patients With Lipedema

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06196619
Enrollment
70
Registered
2024-01-09
Start date
2023-04-01
Completion date
2023-11-01
Last updated
2024-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lipedema, Pain

Keywords

Shear Wave Elastography, Pain, Lipedema

Brief summary

The aim of this study is to evaluate the relationship between disease severity and subcutaneous tissue shearwave elastography findings with pain threshold and quality of life in patients diagnosed with lipedema.

Detailed description

Patients diagnosed with lipedema were divided into 3 stages according to disease severity. Pain level was evaluated with visual analogue scale, pain threshold with algometric measurement, and quality of life with EQ-5D general quality of life scale. All patients underwent measurements using B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography (SWE) imaging of lower limbs at three anatomical levels.

Interventions

DIAGNOSTIC_TESTSWE:B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography at three level

Visual analog scale(VAS):This scale measure in which individuals rate their pain from 0 to 10, with 0 indicating no pain at all and 10 representing the worst pain;pain threshold through algometric measurement; quality of life using the EQ-5D general quality of life scale.

Sponsors

Fatih Sultan Mehmet Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Female patients diagnosed with lipedema

Exclusion criteria

* under 18 years of age, * Patients with edema of cardiac or nephrogenic origin, diabetes mellitus, thyroid dysfunction, patients with lymphedema or chronic venous insufficiency, oncology patients, * individuals with polyneuropathy, radiculopathy, or advanced degenerative diseases affecting the extremities within the last 6 months, based on clinical findings and medical history. * patients using antiepileptics and antidepressants, * individuals unable to cognitively tolerate participation in the study were also excluded.

Design outcomes

Primary

MeasureTime frameDescription
Subcutaneous elastic modulus with shear wave elastography (SWE) imaging of lower limbs1 dayMeasurements using B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography (SWE) imaging of lower limbs at three anatomical levels.
Visual analog scale(VAS)1 dayPain levels were assessed using the visual analog scale(VAS)
Algometric measurement1 dayPain threshold through algometric measurement
EQ-5D general quality of life scale.1 dayquality of life using the EQ-5D general quality of life scale.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026