Chronic Venous Insufficiency
Conditions
Keywords
edema, pain, venous insufficiency, quality of life, respiratory function tests, maximal respiratory pressures, exercise capacity
Brief summary
In the literature, it is still unclear whether individuals with chronic venous insufficiency are affected by edema, pain, respiratory muscle strength, respiratory functions, functional capacity, lower extremity strength and quality of life compared to asymptomatic healthy individuals and if there is a deterioration in these parameters, its level is still unclear. For this reason, in this study it was aimed to investigate edema, pain, respiratory muscle strength, respiratory function, functional capacity, lower extremity strength and quality of life in individuals with chronic venous insufficiency and asymptomatic healthy individuals and to compare these parameters between the two groups.
Detailed description
Chronic Venous Insufficiency affects approximately 30% of the global population and its main symptoms are pain, edema, throbbing, feeling of heaviness in the extremities, itching, varicose veins and tissue changes. Pain in CVI is a chronic condition that negatively affects the quality of life due to physical function and limitation of movement. Limitation of ankle movement in CVI is one of the factors that increase edema and venous severity. Researches investigating pulmonary function in chronic venous insufficiency are very limited. For this reason, in this study it was aimed to investigate edema, pain, respiratory muscle strength, respiratory function, functional capacity, lower extremity strength and quality of life in individuals with chronic venous insufficiency and asymptomatic healthy individuals and to compare these parameters between the two groups.
Interventions
None listed
Sponsors
Izmir Democracy University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
for individuals with chronic venous insufficiency: * Being diagnosed with chronic venous insufficiency * Being in one of the C1, C2, C3, C4, C5 stages according to the 'Clinical, Etiologic, Anatomic, Pathophysiologic' (CEAP) scale * Volunteering to participate in the study * 18 years of age or older
Exclusion criteria
for individuals with chronic venous insufficiency: * Presence of arterial disease, * The presence of advanced cardiorespiratory diseases, * Orthopaedic and neurological disorders affecting walking, * Presence of acute ulcers (\< 3 months) and diabetic ulcers, * Being pregnant. * History of deep vein thrombosis, * Presence of active infection Inclusion criteria for asymptomatic healthy individuals: * 18 years of age and older * Volunteering to participate in the study * Individuals who can understand and answer questionnaires and measurements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximal inspiratory pressure (MIP) | through study completion, an average of 1 year | The MIP which shows respiratory muscle strength will be evaluated using a portable mouth pressure measuring device based on American Thoracic Society and European Respiratory Society criteria. |
| Maximal expiratory pressure (MEP) | through study completion, an average of 1 year | The MEP which shows respiratory muscle strength will be evaluated using a portable mouth pressure measuring device based on American Thoracic Society and European Respiratory Society criteria. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total quality of life score evaluated by Chronic Venous Disease Quality of Life Questionnaire | through study completion, an average of 1 year | The score will be evaluated using Chronic Venous Disease Quality of Life Questionnaire. Each question is scored on a 5-item Likert scale. Higher scores indicate better quality of life. |
| Forced vital capacity (FVC) | through study completion, an average of 1 year | Pulmonary function (Forced vital capacity (FVC) will be evaluated with a spirometer. |
| Forced expiratory volume in the first second (FEV1) | through study completion, an average of 1 year | Pulmonary function (Forced expiratory volume in the first second (FEV1) will be evaluated with a spirometer. |
| FEV1 / FVC | through study completion, an average of 1 year | Pulmonary function (FEV1 / FVC) will be evaluated with a spirometer. |
| The distance of six-minute walk test | through study completion, an average of 1 year | The six-minute walk test (6-MWT) will be performed according to the criteria of the American Thoracic Society for the evaluation of aerobic capacity. |
| Peak flow rate (PEF) | through study completion, an average of 1 year | Pulmonary function (Peak flow rate (PEF) will be evaluated with a spirometer. |
| edema | through study completion, an average of 1 year | Edema in the lower extremity will be evaluated by measuring the circumference using a tape measure. |
| Pain Intensity measured with the Numerical Rating Scale. | through study completion, an average of 1 year | Pain intensity will be measured with the Numerical Rating Scale. This scale expresses the severity of pain with integers from 0 (no pain) to 10 (the worst possible pain). |
| Flow rate 25-75% of forced expiratory volume (FEF 25-75%) | through study completion, an average of 1 year | Pulmonary function (Flow rate 25-75% of forced expiratory volume (FEF 25-75%) will be evaluated with a spirometer. |
| Lower extremity strength | through study completion, an average of 1 year | To determine lower extremity strength and functional mobility, the 30-second Sit-Up Test will be used in the chair. |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORECEM ÖZDEMİR
Dokuz Eylul University
PRINCIPAL_INVESTIGATOREMEK NAZIM EKER
Dokuz Eylul University
PRINCIPAL_INVESTIGATORANIL GİRGİN
Dokuz Eylul University
STUDY_DIRECTORGÜLŞAH BARĞI, Assoc. Dr.
Izmir Democracy University
PRINCIPAL_INVESTIGATORÖZLEM ÖZLEM ÇİNAR ÖZDEMİR, Assoc. Dr.
Izmir Democracy University
PRINCIPAL_INVESTIGATORCEMRE GÖRÜNMEZOĞLU, MSc
Izmir Democracy University
PRINCIPAL_INVESTIGATORSADIK KIVANÇ METİN, Prof. Dr.
Dokuz Eylul University
Outcome results
None listed