The Impact of Arnica Montana Following the Surgical Extraction of Impacted Third Molars

The Impact of Arnica Montana on Postoperative Pain, Swelling and Trismus Following the Surgical Extraction of Impacted Third Molars: A Split Mouth Randomized Clinical Double Blinded Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06193720

Enrollment

Registered

2024-01-05

Start date

2022-02-03

Completion date

2023-08-20

Last updated

2024-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edema, Pain, Trismus

Brief summary

Aim: The aim of this study is to evaluate the action of the homeopathic plant Arnica Montana on postoperative edema, pain and trismus after surgical extraction of impacted wisdom teeth. Materials and Methods: The study is a double-blinded clinical trial recruiting patients undergoing surgical extraction of symmetrically impacted maxillary or mandibular third molars (right and left side). Patients receive alternately and randomly the verum (Arnica Montana 12 CH) or the placebo, in the form of capsules, to be taken 1 day prior to surgery and for 7 days postoperatively. Clinical parameters are collected and include: pain score, maximum mouth opening and facial measurements to assess edema's intensity.

Interventions

DRUGArnica montana

Assess the effect of arnica montana on pain, swelling ans trismus after impacted third molar surgery

OTHERPlacebo

Patients will take placebo drug after surgeries

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

16 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Symmetrically impacted bilateral third molars (mandibular or maxillary). * Young patients aged between 16 and 40 years old. * No consumption of tobacco or coffee. * Consent to the terms and conditions of the study. * Good oral hygiene. * ASA 1.

Exclusion criteria

* Not symmetrically impacted third molars * Patients with health problems

Design outcomes

Primary

Measure	Time frame	Description
Pain VSA	at 0,1,2,3,4,5,6,7 days after surgery	Assessment of pain on visual analogue scale (between 0 and 10, 0 being no pain at all and 10 being the worst pain)
Amount of face Swelling	at 0,2,7 days after surgery	Assessment of swelling after the intervention using a flexible ruler to measure the distance between fixed fixed reference points marked on the face: * G: Mandibular angle * C: External canthus * T: Tragus * S: Sub-nasal point * P: Pogonion
Trismus intensity	at 0,2 and 7 days after surgery	Assessment of limitation of mouth opening after intervention between the incisal edges of the maxillary and the mandibular central incisors using a vernier caliper

Countries

Lebanon

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026