Fertility
Conditions
Keywords
Fertility
Brief summary
Collection and conservation of human biological material from fertile subjects, i.e. men with previous parenthood (normospermic men, natural fathers).
Detailed description
The project aims to collect biological material derived both from surgical resections of the most common urological tumors and from peripheral blood or other biological fluids such as urine or seminal fluid when available. The objective of the study is to establish a biobank of human biological material, which will allow access to samples of extreme value for the pathophysiological study of the tumor, its origin, mechanisms and markers of progression, as well as the creation of this collection it will represent an extremely valuable tool for the study of individual response to therapies.
Interventions
OTHERObservation of biological characteristics of fertile men
Sampling in outpatient settings, after biopsy or after surgery and collection of biological samples in fertile subjects
Sponsors
IRCCS San Raffaele
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 60 Years
Inclusion criteria
* Normospermic male individuals * Naturally fertile male individuals * Male individuals \> 18 years
Exclusion criteria
* Non-normospermic male individuals * Male individuals who are not naturally fertile * Male individuals \< 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prognostic role of the biological material | Baseline | Biological signature in fertile men predicting potential therapeutic, prognostic and diagnostic biomarkers |
Countries
Italy
Outcome results
None listed