Dry Skin; Eczema, Skin Hyperpigmentation
Conditions
Brief summary
Niacinamide in lower concentrations has been recognized as a cosmetic ingredient with hydrating properties. Therefore, aim was to test the efficacy and safety of niacinamide cosmetic preparation in A Randomized, Controlled Trial.
Detailed description
Skin hydration (as use of hydrating cosmetic ingredients) is one of the most interventions for healthy skin and skin barrier function. Therefore, cosmetic ingredients used for this purpose should be examined for their efficacy.
Interventions
OTHERmiss alice face it you love me serum
Facial serum with niacinamide, plant-based collagen and peptides will be applied by each participant to the treatment site according to randomization protocol every evening
OTHERNo treatment (usual skincare rutine)
No treatment (usual skincare rutine)
Sponsors
University of Split, School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* healthy volunteers who gave written informed consent
Exclusion criteria
* skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TEWL assessment with Courage Khazaka probe | through study completion, an average of 1 year | Transepidermal water loss |
| Hydration assessment with corneometer probe | through study completion, an average of 1 year | stratum corneum hydration |
| pigmentation assessment with mexameter probe | through study completion, an average of 1 year | erythema and melanin |
| skin oiliness assessment with sebumeter probe | through study completion, an average of 1 year | sebum level |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| subjective opinion of participants | through study completion, an average of 1 year | participants notes on skin rection |
Countries
Croatia
Contacts
Primary ContactJosipa Bukic
Outcome results
None listed