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Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery

Investigation of the Effect of Proximal and Distal Adductor Canal Block on Pain Control and Functional Mobility in Total Knee Prosthesis Surgery Performed Under Spinal Anesthesia

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06188806
Enrollment
78
Registered
2024-01-03
Start date
2023-11-10
Completion date
2026-03-30
Last updated
2025-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

adduktor canal block,knee artroplasti,postoperative pain

Brief summary

to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.

Detailed description

This prospective randomized trial is randomly divided into 3 groups using the method. Total knee arthroplasty is performed by the same surgical team. is applied. The patients were divided into proximal ACB applied, distal ACB applied and control groups.

Interventions

OTHERADDUKTOR CANAL BLOCK

All patients who will undergo adductor canal block are sedated with midazolam 0.03 mg/kg in the preoperative preparation room, after standard monitoring. After 2-3 ml skin infiltration with 2% lidocaine under sterile conditions, a block is applied under USG guidance.To verify block success, sensory function is assessed by pinprick testing along the saphenous nerve distribution by comparing the pinprick sensation to the unaffected limb.All patients are monitored in the operating room and in a sitting position, 10-20 mg (2-4 ml) of heavy marcaine (0.5% bupivacaine hydrochloride and dextrose monohydrate) is applied to the subarachnoid space by entering the L3-4 or L4-5 space with a 25-gauge Whitrace needle.For postoperative multimodal analgesia, which is routinely applied to all patients, intravenous PCA (patient controlled analgesia )tramadol and paracetamol 10 mg / kg iv (8 hours apart) will be given.

OTHERCONTROL GROUP

No nerve block procedure is applied to patients.All patients are monitored in the operating room and in a sitting position, 10-20 mg (2-4 ml) of heavy marcaine (0.5% bupivacaine hydrochloride and dextrose monohydrate) is applied to the subarachnoid space by entering the L3-4 or L4-5 space with a 25-gauge Whitrace needle.For postoperative multimodal analgesia, which is routinely applied to all patients, intravenous PCA (patient controlled analgesia) tramadol 50 mg at 10 mg / hour basal rate after loading (20 mg bolus dose + 30 minutes lock time) and paracetamol 10 mg / kg iv (8 hours apart) will be given.

Sponsors

Umraniye Education and Research Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

three groups Group 1: proximal ACB (n:26) Group 2: distal ACB(n:26) Group 3: Control group (n:26)

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* Medications for unilateral TKA surgery * Patients aged 18-85 * ASA 1-3

Exclusion criteria

* Patients under 18 years of age and over 85 years of age * Patients with ASA 4 and above * Patients with cognitive impairment * Patients with application site infection * Patients allergic to local anesthesia * Patients receiving anticoagulant therapy * Patients with bleeding diathesis * Patients with chronic opioid or substance use * Patients with insulin-dependent diabetes mellitus * patients with neuropathy * patients with hepatic or renal failure * Patients who do not accept the procedure to be applied

Design outcomes

Primary

MeasureTime frameDescription
VISUAL ANALOGUE SCALE(VAS)POSTOPERATIVE 6, 12 AND 24 HOURSVAS pain score was evaluated as no pain (score=0) and worst pain (score=10) and was divided into 3 groups according to the World Health Organization's pain intensity scale: score \<3 mild pain, 3-6 mild-moderate. degree pain and \>6 moderate-severe pain.

Secondary

MeasureTime frameDescription
first mobilization timewithin postoperative 24 hoursThe first postoperative mobilization hours of the patients will be recorded.
length of hospital stayONE WEEKThe time between patients' admission and discharge will be recorded.
opioid usewithin postoperative 24 hoursIntravenous PCA will be applied to each patient and the total tramadol dose spent will be calculated.intravenous PCA (patient controlled analgesia) tramadol 50 mg at 10 mg / hour basal rate after loading (20 mg bolus dose + 30 minutes lock time)

Countries

Turkey (Türkiye)

Contacts

Primary ContactZeliha TUNCEL
zelihalara@yahoo.com+90 505 357 74 83

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026