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Intraoperative Different Fluid Therapy Protocols

The Effects Of Intraoperative Different Fluid Therapy Protocols On Postoperative Renal Functions

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06188299
Enrollment
60
Registered
2024-01-03
Start date
2022-01-20
Completion date
2023-05-15
Last updated
2024-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Fluid Management

Keywords

Liberal Fluid Therapy, Restrictive Fluid Therapy

Brief summary

We aimed to evaluate the relationship between different intraoperative fluid therapy protocols and postoperative renal damage and mortality.

Detailed description

Sixty patients who 18-65 age and underwent pancreatic surgery in our hospital were included in the study. They were divided into two groups as liberal fluid therapy (Group 1, n=30) and targeted fluid therapy (Group 2, n=30).

Interventions

OTHERRestricted Fluid Administration

Restrictive fluid administration generally consists of partial or no replacement for the intravascular expansion from anesthesia, in which case vasopressors are usually administered, no replacement for the third space loss, and only partial replacement for deficits from preoperative fasting.

Sponsors

Ankara City Hospital Bilkent
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Outcomes Assessor)

Intervention model description

Liberal Fluid Therapy Group and Targeted Fluid Therapy Groups.

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Planned pancreatic surgery

Exclusion criteria

* No

Design outcomes

Primary

MeasureTime frameDescription
AKI72 HourPostoperative Renal Injury
Mortality72 HourIntraoperative and Postoperative Mortality Rate

Secondary

MeasureTime frameDescription
Blood LossIntraoperative periodIntraoperative total blood loss

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026