Bladder Disease
Conditions
Keywords
Botulinum Toxin, overactive bladder, interstitial cystitis
Brief summary
Botulinum toxin injection into the bladder is used in current practice in urological diseases such as overactive bladder or interstitial cystitis. As far as is known, botulinum toxin injection sites have not been clearly defined. In this study, investigators are planning to compare botulinum toxin effectiveness with different injection site maps.
Interventions
OTHERIntravesical Botulinum Toxin
Botulinum Toxin injections will be made into the bladder.
Sponsors
Başakşehir Çam & Sakura City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Older than 18 years * Interstitial cystitis patients * Overactive bladder
Exclusion criteria
* younger than 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overactive bladder-V8 questionnaire will be used for efficacy of treatment. | Estimated 1 month for every patient after treatment. | The questionnaire contains 8 questions and every question may be scored between 0 and 5. Additionally, male gender get 2 points more. Therefore, a patient may be get between 0 and 42 points. More score means worse complaint. |
| Urodynamics test will be assessed for efficacy of treatment. | Estimated 1 month for every patient after treatment. | Possible bladder contractions and residual volume will be measured in urodynamic testing to demonstrate effectiveness after treatment. The lack of pathological bladder contractions and normal residual urine mean better for patient and, show improving. |
Outcome results
None listed