Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06184620

Enrollment

263

Registered

2023-12-28

Start date

2020-12-01

Completion date

2023-03-30

Last updated

2023-12-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Angle Closure Glaucoma

Keywords

primary angle closure glaucoma, UBM, lens zonule

Brief summary

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

Detailed description

Patients clinically diagnosed with Primary angle-closure glaucoma (PACG) and normal control patients from December 2020 to January 2022 were enrolled in this study.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

47 Years to 91 Years

Healthy volunteers

Yes

Inclusion criteria

* The depth of the anterior chamber is normal, and the whole corner of the chamber is open; * The cup-to-plate ratio is less than 0.5; * No family history of glaucoma.

Exclusion criteria

* Previous history of trauma or internal eye surgery in both eyes or one eye; * Used pilocarpine, atropine and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week; * Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.; * Can not cooperate with UBM and Angle scopy; * Refuse to participate in this researcher.

Design outcomes

Primary

Measure	Time frame	Description
Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),	before operation	Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),
Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions	before operation	Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions

Countries

China

Outcome results