Induction of Labor Affected Fetus / Newborn, Pregnancy Late
Conditions
Keywords
Late-term pregnancy, body mass index, age, oral misoprostol, cervical ripening, induction of labor
Brief summary
To evaluate the effect of maternal age and body mass index (BMI) on oral misoprostol induction of labor for late-term pregnancies.
Interventions
Oral misoprostol for induction of labor in late term pregnancies
Sponsors
Study design
Eligibility
Inclusion criteria
* Late term pregnancies out of labor, * Bishop score \< 7
Exclusion criteria
* labor (defined as presence of at least three painful uterine contractions every ten minutes), * uterine tachysystole (\>5 contractions within 10 minutes for two consecutive 10-minute periods), * hypertonic uterus, * abnormal CTG, * contraindications to vaginal delivery (fetal malpresentation such as breech presentation or transverse situation, fetal macrosomia, abnormally implanted placenta, active genital herpes infection, cervical cancer), * patients with parity \> 4, * medical contraindication to misoprostol (asthma, glaucoma), * women with previous hysterotomies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Safety and tolerability of misoprostol for induction of labor | 290 days of pregnancy | Efficacy induction of labor for late term pregnancies according to age and BMI |
Countries
Italy