Knee Arthropathy
Conditions
Keywords
knee arthroplasty, acute postoperative pain, persistent post surgical pain, regional anesthesia
Brief summary
Patients undergone total knee replacement are randomized to receive a fast track regional anesthesia protocol or a traditional regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this latter technique may reduce persistent postoperative pain six months after surgery
Detailed description
Patients undergone to primary total knee replacement with spinal anesthesia are randomized to receive a continuous adductor canal block infusion + an ipack block or a continuous femoral nerve block + a continuous sciatic nerve block just at the end of surgery. Both group will receive a multimodal analgesia with paracetamol, ketorolac, desametasone and morphine as a rescue.
Interventions
PROCEDUREcontinuous peripheral nerve block
continuous regional anesthesia in total knee replacement
Sponsors
Policlinico di Monza SpA
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* primary total knee replacement with a written informed consent
Exclusion criteria
* Allergy to local anesthetics or any drugs involve in the study * Controindication to regional anesthesia * chronic use of opioids * BMI \> 35 kg m2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Persistent post surgical pain | 0-6-month | Numeric rating score (0-10) over 4 at the follow up 6-month after total knee replacement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| acute postoperative pain | 0-72 hours | Numeric rating score (0-10) over 4 in POD0, POD1, POD2, POD3 |
| Morphine requirement | 0-72 hours | total morphine administration via PCA in POD0, POD1, POD2, POD3 |
Countries
Italy
Contacts
Primary ContactGianluca Cappelleri, MD
Backup ContactGianluca Perseghin, MD
Outcome results
None listed