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Post-Resuscitation Pneumothorax - Analysis of Incidence, Risk Factors and Outcome Relevance

Pneumothorax After Cardiopulmonary Resuscitation Following Out-of-Hospital Cardiac Arrest - Analysis of Incidence, Risk Factors and Impact on Outcome

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06182007
Enrollment
237
Registered
2023-12-26
Start date
2020-02-02
Completion date
2022-12-31
Last updated
2023-12-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest, Pneumothorax, Resuscitation

Brief summary

In this retrospective study, the investigators seek to investigate the incidence of pneumothorax following possible risk factors, and elucidate its association with outcomes.

Detailed description

This is a retrospective analysis of routine data, collected by a single Emergency Medical System (EMS). Adult patients (≥18 years) hospitalised after Out-of-Hospital Cardiac Arrest (OHCA) who received chest compressions and underwent chest imaging within 12 hours after hospital admission were included. Variables and outcomes ascertained are built up of the core elements of the latest version of the Utstein Resuscitation Registry Template for OHCA. This includes sex, age, aetiology of arrest, response times of the first emergency medical service team and emergency physician, witnessed cardiac arrest, bystander CPR/AED, arrest location, first monitored rhythm, defibrillation time, drugs given, reperfusion attempted and target temperature management. Additional variables studied were pre-existing health status represented by the Pre Emergency Status Assessment (PESA), history of lung disease, no-flow-time (time from collapse until initiation of CPR), use of a mechanical chest compression device and prehospital CPR duration. The primary outcome is incidence of pneumothorax, secondary outcomes are survival to hospital discharge and favourable neurological condition at hospital discharge defined by a cerebral performance category (CPC) of 1 or 2.

Interventions

PROCEDURECardiopulmonary Resuscitation

Cardiopulmonary Resuscitation (Advanced Life Support) according to current guidelines

Sponsors

Auinger, Daniel MD
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Hospitalized after out of hospital cardiac arrest * Chest compressions received * Chest imaging within the first 12 hours of admission

Exclusion criteria

* Traumatic cardiac arrest * Chest trauma/surgery/pneumothorax one month prior to cardiac arrest

Design outcomes

Primary

MeasureTime frame
Presence of pneumothoraxwithin 12 hours of admission

Secondary

MeasureTime frame
Survivalto hospital discharge (up to 2 months)
Cerebral Performance Categoryat hospital discharge (up to 2 months)

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026