Comparison of Quality of Life in Moderate Acne Vulgaris Patients Based on Acne-QoL-INA Using Standard Therapy With and Without Acne Lesions Extraction

Single-Blinded Randomized Controlled Trial: Comparison of Quality of Life in Moderate Acne Vulgaris Patients Based on Acne-QoL-INA Using Standard Therapy With and Without Acne Lesions Extraction

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06181838

Enrollment

Registered

2023-12-26

Start date

2023-08-28

Completion date

2024-01-03

Last updated

2023-12-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris, Quality of Life

Brief summary

This study will compare the quality of life between 2 groups, which are group that receive standard moderate acne therapy in addition of lesion extractions, and the second group which only receive standard moderate acne therapy without lesion extractions.

Detailed description

The group allocation will be randomized. Outcome of the study is the quality of life score based on Acne-QoL-INA questionnaire. The study duration is 8 weeks, consists of baseline visit and 2 follow ups at 4th and 8th weeks.

Interventions

PROCEDURELesion extraction

Tretinoin and benzoil peroxide used concurent in both groups as standard therapy

DRUGTretinoin

Tretinoin and benzoil peroxide used concurent in both groups as standard therapy

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 59 Years

Healthy volunteers

Yes

Inclusion criteria

* Clinically diagnosed as moderate acne vulgaris * Able to read and speak in Indonesia * Indonesian Citizen * Sign the consent form

Exclusion criteria

* Pregnant of breastfeeding women * Acne vulgaris lesion located only outside of face * Experiencing COVID-19 symptoms * Using retinoid acid containing cream or benzoil peroxide in the last 2 weeks * Consume any oral antibiotics in the last 1 month * Injected with intralesional steroid or having acne lesions extracted in the last 2 weeks * Having laser or chemical peeling in the last 1 month

Design outcomes

Primary

Measure	Time frame	Description
Quality of Life Score	Every 4 weeks, measured until 8 weeks	Measured using Acne-QoL-INA questionnaire

Secondary

Measure	Time frame	Description
Acne Grading	Every 4 weeks, measured until 8 weeks	Lehmann classification of Acne Grading

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026