Skip to content

The Impact of Pericardial Closure on the Grafts, in the Context of Coronary Artery Bypass Grafting

The Impact of Pericardial Closure on the Grafts, in the Context of Coronary Artery Bypass Grafting

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06181565
Enrollment
34
Registered
2023-12-26
Start date
2022-01-01
Completion date
2022-10-24
Last updated
2023-12-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bypass Graft Stenosis

Keywords

Cardiac surgery, pericardial closure, grafts, bypass, aortocoronary bypass

Brief summary

Once the pericardium is closed, there is no information on the hemodynamics of the grafts after coronary artery bypass grafting. This would be the reason for different opinions on pericardial closure: some teams do not close the pericardium and others close it. In the department Cardiovascular Surgery of the University Hospital of Saint-Etienne, the Medistim machine is used in routine and the hemodynamic properties of the grafts are recorded immediately after the bypass surgery, before the closure of the pericardium.

Detailed description

The aim of the study is to have hemodynamic information immediately after the closure of the pericardium using the Medistim machine. The prospective study will be conducted on 50 patients, who will be selected consecutively without randomization. The inclusion and exclusion criteria are determined.

Interventions

OTHERDatas of Medistim machine

Datas will be collected by Medistim machine before and after pericardial closure: Flow through the grafts, Resistance on grafts, Pulsatility of the grafts, Systolic and diastolic curves before and after pericardial closure

Sponsors

Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients who will have isolated aortocoronary bypass grafting surgery

Exclusion criteria

* History of thoracic trauma * Severe cyphosis * Severe thoracic deformity (Pectus excavatum) * Pericardial disease * History of radiotherapy * Severe pulmonary disease (emphysema) * Right heart failure * Redo surgery

Design outcomes

Primary

MeasureTime frameDescription
Flow through the graftsMinute : 1, 15Datas will be collected by Medistim machine.

Secondary

MeasureTime frameDescription
Resistance on graftsMinute : 1, 15Datas will be collected by Medistim machine.
Pulsatility of the graftsMinute : 1, 15Datas will be collected by Medistim machine.
Systolic curvesMinute : 1, 15Datas will be collected by Medistim machine.
Diastolic curvesMinute : 1, 15Datas will be collected by Medistim machine.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026