Non-small Cell Lung Cancer Stage I, Surgery
Conditions
Keywords
segmentectomy, lobectomy
Brief summary
Actual indications for stage Ia NSCLC patients suggest lobectomy and lymphadenectomy. On the other hand, recent studies reported non-inferiority of segmentectomy in case of nodule \< 2cm or with ground glass appearance at computed tomography. However, most of these studies did not report specifical analysis on kind of segmentectomy (single or multiple) and kind of lobectomy. Moreover, a specific study on solid nodules only is still missing. For these reasons, the effectiveness of segmentectomy instead lobectomy for every kind of segment or tumor is still to be defined. Aim of this study is to analyze survival outcome in patients underwent single or multiple segmentectomy compared to lobectomy in stage I non small cell lung cancer.
Interventions
None listed
Sponsors
Regina Elena Cancer Institute
Istituto Europeo di Oncologia
University of Pisa
A.O.U. Città della Salute e della Scienza - Molinette Hospital
Azienda Ospedaliera Sant'Andrea
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adenocarcinoma or squamous cell carcinoma * cStage cIA with or without nodal upstaging * lymphoadenectomy * age \> 18 years old * Radical resection * anatomical resection (lobectomy or segmentectomy) * PET CT done
Exclusion criteria
* Nodal or distant metastasis confirmed before surgery * Pure solid GGO * Follow up \< 12 months * Bilobectomy/pneumonectomy * Trans fissure tumor * Multiple lung tumors
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| disease free survival | 1 YEAR | Time between surgery and recurrence appearance |
Countries
Italy
Outcome results
None listed