Knee Osteoarthritis
Conditions
Keywords
rehabilitation, knee, osteoarthritis
Brief summary
A randomized clinical trial to evaluate the effectiveness of an instrumental rehabilitation protocol compared with standard protocol In patients with knee osteoarthritis.
Detailed description
This is a randomized clinical trial designed to compare two intervention aimed at reducing and improving knee function in patients with knee osteoarthritis \- sixty subjects suffering from knee osteoarthritis will be recruited; 30 per group. A: instrumental rehabilitation B:standard rehabilitation All patients who meet the clinical inclusion and exclusion criteria will have a standard radiography * selected patients will be invited to participate and will be informed of the purpose and conduct of the study * patients will be randomized to either the instrumental rehabilitation programme groupe or the standard rehabilitation group * patients in both groups will have a protocol that will be extended over 6 weeks * participants will be assessed primarily for function and pain, as well as other secondary endpoints , at baseline at 3 weeks and at 12 weeks.
Interventions
OTHERrehabilitation
For the experimental group: Isokinetic training Antigravity treadmill Posturography For the control group: Patients will receive a standard rehabilitation prescription comprising: Physiotherapy , muscle stretching and strengthening , proprioceptive exercises, and self-programmed
Sponsors
Ibn Sina University Hospital, Rabat, Morocco
Mohammed V Souissi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Masking description
Masking is a technique used to keep treatment information indisclosed to the study participants while allowing researchers and treatment administration to know this information: study participants are not informed about the treatment they are receiving, they do not know whether they are receiving the experimental treatment under investigation or if they are in the control group , which may receive a placebo or standard treatment . This helps reduce potential bias related to participant expectations
Intervention model description
A randomized single blind clinical trial is a research study design used to evaluate the effectiveness of a medical intervention or treatment. In this type of trial, participants are randomly assigned to one of two a more groups, one groupe receives the experimental treatment, while the other group may receive a placebo or standard treatment, depending on the study's design \- the term single blind refers to the fact that , in this trial the participants do not know whether they are receiving the experimental treatment or a control treatment this is done to minimize the potential for bias in reporting their symptoms or outcomes
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patients with radiologically confirmed uni/ bilateral gonarthrosis
Exclusion criteria
* Will be excluded from our study: * Subjects with congestive gonarthrosis (joint effusion at clinical examination). * Patients followed for chronic inflammatory rheumatism. * Patients who are candidates for surgery for knee osteoarthritis * Patients with a pathology causing a limitation in walking distance apart from gonarthrosis. * Amputees of one or both lower limbs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Le Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) | 12 weeks | The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is an assessment tool developed to measure pain, stiffness, and physical function in individuals with osteoarthritis, primarily in the knee and hip. Patients' responses to each question are typically scored on a scale ranging from 0 to 4, where 0 signifies no symptoms and 4 signifies severe symptoms. Scores obtained in each subscale can be combined to provide a total score or used individually to assess specific aspects of osteoarthritic symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| muscle testing of hamstring and quadriceps | 12 weeks | Muscle testing is employed to assess hamstring and quadriceps strength on a qualitative scale ranging from 0 to 5 |
| time up and go | 12 weeks | is utilized to evaluate patient mobility and balance, measured in seconds,Less than 13.5 seconds: Low risk of falling; the person has good walking speed and functional mobility. 13.5 seconds or more: High risk of falling; the person does not have good walking speed or functional mobility. |
| the Visual Analog Scale | 12 weeks | the Visual Analog Scale (VAS), a graded scale ranging from 0 to 100 millimeters, 0 no pain and 100 severe pain |
| Joint amplitude measurements | 12 weeks | using a goniometer to evaluate the extent of knee flexion and extension |
| results of balance plateform assessement | 12 weeks | the surface area of the confidence ellipse in square millimeters , length of the stabilogram in millimeters, x and y coordinates of the center of pressure in millimeters |
| muscle testing of hamstring and quadriceps using an isokinetic dynamometer | 12 weeks | peak torque in newtons and body weight in newtons per kilogram |
| walking test | 12 weeks | support symmetry in percentage and step length in centimeters |
| quality of life index | 12 weeks | the SF12 questionnaire is administered to assess quality of life,The minimum value is 0, and the maximum value is 100,Scores above 50 indicate a better-than-average health-related quality of life, while scores below 50 suggest below-average health. |
Countries
Morocco
Contacts
Primary ContactHouda EL Moudane, phd student
Outcome results
None listed