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Encouraging Healthy and Sustainable Dietary Substitutions

Encouraging Healthy and Sustainable Dietary Substitutions: A Randomized Experiment With Emerging Adults

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06175026
Enrollment
1753
Registered
2023-12-18
Start date
2024-01-22
Completion date
2024-02-02
Last updated
2024-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food Selection

Keywords

health, environment, sustainability, food choices, dietary substitutions, diet, emerging adults

Brief summary

The aim of this study is to examine emerging adults' responses to dietary substitution messages about health, the environment, or both health and the environment.

Detailed description

This online study will examine emerging adults' responses to dietary substitution messages about 4 different topics. Participants will be randomized to 1 of 4 topic arms: 1) Control (neutral topic, not related to health or the environment); 2) Health topic; 3) Environment topic; 4) Health and Environment topic. Participants will view messages about each of 4 dietary substitutions: replacing red meat with chicken or vegetarian options; replacing dairy milk with non-dairy milk; replacing juice with whole fruit; and replacing sugar-sweetened beverages with water. For each dietary substitution, participants will view 2 messages about their assigned topic, with the 2 messages shown in random order. Participants will rate each message on perceived message effectiveness (primary outcome).

Interventions

BEHAVIORALHealth messages

Participants view messages about the health impacts of certain dietary substitutions.

BEHAVIORALEnvironmental messages

Participants view messages about the environmental impacts of certain dietary substitutions.

BEHAVIORALHealth and environmental messages

Participants view messages about the health and environmental impacts of certain dietary substitutions.

BEHAVIORALNeutral messages

Participants view neutral messages unrelated to the health and environmental impacts of certain dietary substitutions.

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)
CollaboratorNIH
Stanford University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* Age between 18-25 years * Reside in the United States * Ability to complete a survey in English

Exclusion criteria

* Older than 25 years; younger than 18 years * Reside outside of the United States * Unable to complete a survey in English

Design outcomes

Primary

MeasureTime frameDescription
Perceived Message EffectivenessSurvey questions administered after participant viewed each message; overall survey took up to 20 minutesParticipants will rate each message on perceived message effectiveness (PME) for encouraging participants to make the target dietary substitution. PME will be assessed with 4 items \[the text shown in brackets will be tailored to each substitution\]: 1. How much does this message discourage you from wanting to \[eat beef and pork / drink juice / drink cow's milk / drink sugary drinks\]? 2. How much does this message make \[eating beef and pork, etc.\] seem unpleasant to you? 3. How much does this message make you concerned about the effects of \[eating beef and pork, etc.\]? 4. How much does this message make you want to \[eat chicken or vegetarian options instead of beef and pork, etc.\]? The response options for each item are: 1=Not at all, 2=Very little, 3=Somewhat, 4=Quite a bit, 5=A great deal. Investigators will average responses to these 4 items to create a perceived message effectiveness score. Higher scores indicated higher perceived message effectiveness.

Countries

United States

Participant flow

Participants by arm

ArmCount
Health Messages
Messages shown will be related to the health impacts of making certain dietary substitutions (replacing beef with chicken and vegetarian entrees; replacing juice with whole fruit; replacing dairy milk with non-dairy milk; replacing sugar-sweetened beverages with water). Health messages: Participants view messages about the health impacts of certain dietary substitutions.
437
Environment Messages
Messages shown will be related to the environmental impacts of making certain dietary substitutions (replacing beef with chicken and vegetarian entrees; replacing juice with whole fruit; replacing dairy milk with non-dairy milk; replacing sugar-sweetened beverages with water). Environmental messages: Participants view messages about the environmental impacts of certain dietary substitutions.
441
Health and Environment Messages
Messages shown will be related to the health and environmental impacts of making certain dietary substitutions (replacing beef with chicken and vegetarian entrees; replacing juice with whole fruit; replacing dairy milk with non-dairy milk; replacing sugar-sweetened beverages with water). Health and environmental messages: Participants view messages about the health and environmental impacts of certain dietary substitutions.
424
Neutral Messages
Messages shown will be neutral and unrelated to the health or environmental impacts of making certain dietary substitutions (replacing beef with chicken and vegetarian entrees; replacing juice with whole fruit; replacing dairy milk with non-dairy milk; replacing sugar-sweetened beverages with water). Neutral messages: Participants view neutral messages unrelated to the health and environmental impacts of certain dietary substitutions.
430
Total1,732

Baseline characteristics

CharacteristicHealth MessagesEnvironment MessagesHealth and Environment MessagesNeutral MessagesTotal
Age, Categorical
<=18 years
0 Participants0 Participants0 Participants0 Participants0 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
437 Participants441 Participants424 Participants430 Participants1732 Participants
Age, Continuous21.8 years
STANDARD_DEVIATION 2.2
22.0 years
STANDARD_DEVIATION 2.3
21.9 years
STANDARD_DEVIATION 2.2
21.7 years
STANDARD_DEVIATION 2.3
21.8 years
STANDARD_DEVIATION 2.2
Ethnicity (NIH/OMB)
Hispanic or Latino
55 Participants60 Participants80 Participants76 Participants271 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
382 Participants381 Participants344 Participants354 Participants1461 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
American Indian or Alaska Native
6 Participants5 Participants7 Participants11 Participants29 Participants
Race (NIH/OMB)
Asian
17 Participants9 Participants17 Participants9 Participants52 Participants
Race (NIH/OMB)
Black or African American
55 Participants50 Participants58 Participants56 Participants219 Participants
Race (NIH/OMB)
More than one race
28 Participants30 Participants20 Participants23 Participants101 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
2 Participants0 Participants3 Participants1 Participants6 Participants
Race (NIH/OMB)
Unknown or Not Reported
10 Participants15 Participants17 Participants15 Participants57 Participants
Race (NIH/OMB)
White
319 Participants332 Participants302 Participants315 Participants1268 Participants
Region of Enrollment
United States
437 participants441 participants424 participants430 participants1732 participants
Sex/Gender, Customized
Gender
Female
226 Participants226 Participants207 Participants215 Participants874 Participants
Sex/Gender, Customized
Gender
Male
196 Participants210 Participants207 Participants205 Participants818 Participants
Sex/Gender, Customized
Gender
Non-binary or another gender
15 Participants5 Participants10 Participants10 Participants40 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
EG003
affected / at risk
deaths
Total, all-cause mortality
0 / 4370 / 4410 / 4240 / 430
other
Total, other adverse events
0 / 4370 / 4410 / 4240 / 430
serious
Total, serious adverse events
0 / 4370 / 4410 / 4240 / 430

Outcome results

Primary

Perceived Message Effectiveness

Participants will rate each message on perceived message effectiveness (PME) for encouraging participants to make the target dietary substitution. PME will be assessed with 4 items \[the text shown in brackets will be tailored to each substitution\]: 1. How much does this message discourage you from wanting to \[eat beef and pork / drink juice / drink cow's milk / drink sugary drinks\]? 2. How much does this message make \[eating beef and pork, etc.\] seem unpleasant to you? 3. How much does this message make you concerned about the effects of \[eating beef and pork, etc.\]? 4. How much does this message make you want to \[eat chicken or vegetarian options instead of beef and pork, etc.\]? The response options for each item are: 1=Not at all, 2=Very little, 3=Somewhat, 4=Quite a bit, 5=A great deal. Investigators will average responses to these 4 items to create a perceived message effectiveness score. Higher scores indicated higher perceived message effectiveness.

Time frame: Survey questions administered after participant viewed each message; overall survey took up to 20 minutes

ArmMeasureValue (MEAN)Dispersion
Health MessagesPerceived Message Effectiveness2.94 score on a scaleStandard Deviation 0.95
Environment MessagesPerceived Message Effectiveness2.83 score on a scaleStandard Deviation 1.01
Health and Environment MessagesPerceived Message Effectiveness2.98 score on a scaleStandard Deviation 0.93
Neutral MessagesPerceived Message Effectiveness1.69 score on a scaleStandard Deviation 0.98
Comparison: The null hypothesis was that the health messages would not elicit different levels of perceived message effectiveness compared to the neutral messages.p-value: <0.00195% CI: [1.13, 1.37]Mixed Models Analysis
Comparison: The null hypothesis was that the environment messages would not elicit different perceived message effectiveness than the control messages.p-value: <0.00195% CI: [1.03, 1.26]Mixed Models Analysis
Comparison: The null hypothesis was that the health and environment messages would not elicit different perceived message effectiveness than the control messages.p-value: <0.00195% CI: [1.17, 1.41]Mixed Models Analysis
p-value: 0.189295% CI: [-0.018, 0.223]Mixed Models Analysis
p-value: 0.4795% CI: [-0.17, 0.08]Mixed Models Analysis
p-value: 0.05195% CI: [-0.27, -0.03]Mixed Models Analysis

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026