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Study of a Series of Patients Treated for Retrograde Cricopharyngeal Muscle Dysfunction Syndrome

Study of a Series of Patients Treated for Retrograde Cricopharyngeal Muscle Dysfunction Syndrome

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06174831
Acronym
R-CPD-Syndrome
Enrollment
30
Registered
2023-12-18
Start date
2023-02-01
Completion date
2024-01-19
Last updated
2023-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deglutition Disorders

Keywords

Deglutition Disorders, Dysphagia, cricopharyngeus muscle, Circular sphincter, Esophagus, Botulinum toxin

Brief summary

R-CPD syndrome (Retrograde Cricopharyngeal Dysfunction syndrome) is an inability to burp. It is a syndrome whose diagnosis is clinical, and for which there is effective treatment. Recently treated in the United States (first publication in 2019), this syndrome affects many patients in France and is currently unknown. This study concerns a series of patients treated at the University Hospitals of Strasbourg for a syndrome of retrograde dysfunction of the cricopharyngeus muscle having been treated by injection of botulinum toxin into the cricopharyngeus muscle.

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Major subject (≥18 years old) * Subject treated by injection of botulinum toxin into the cricopharyngeal muscle after having had a diagnosis of R-CPD in consultation between January 1, 2022 and December 31, 2022 * Subject not opposing the reuse of their data for the purposes of this research.

Exclusion criteria

* Subject having expressed opposition to participating in the study, * Subject under judicial protection * Subject under guardianship or curatorship

Design outcomes

Primary

MeasureTime frameDescription
Retrospective description of the characteristics of a series of patients treated for dysphagia syndromeThrough study completion, an average of 2 monthsRetrospective study of medical files of patients treated in HUS between January 1, 2022 and December 31, 2022

Countries

France

Contacts

Primary ContactChristian DEBRY, MD, PhD
christian.debry@chru-strasbourg.fr33 3 88 12 76 44

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026