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Improvements by a Protein-rich Plant-based Diet and Resistance Exercise Program for Active Ageing

Improvements by a Protein-rich Plant-based Diet and Resistance Exercise Program for Active Ageing

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06172725
Acronym
IMPACT
Enrollment
110
Registered
2023-12-15
Start date
2024-03-11
Completion date
2025-06-27
Last updated
2026-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Protein Intake

Brief summary

High-protein intake and physical activity are important approaches to preserve muscle mass. Consuming high levels of high-quality proteins to preserve muscle mass is challenging with a plant-based diet. Healthy, older participants will follow a twelve-week high-protein vegetarian diet or high-protein omnivorous diet both in combination with a resistance training program. The change in protein intake and muscle mass will be assessed.

Interventions

All participants will follow a resistance exercise program (3/week), which is personally guided by trainers.

Sponsors

Amsterdam University of Applied Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Aged 55 years or older * BMI 18.5-30 kg/m2 * Living independently * Ability and willingness to comply with the protocol * Written an informed consent * Consent of the study physician

Exclusion criteria

* Alcohol abuse (more than 14 glasses per week (women) or more than 21 glasses per week (men)) or drug abuse in the opinion of the study physician (CBS et al., 2017) * Inability to understand the Dutch language * Cognitive impairment (MMSE more than 25) * Diagnosed chronic disease that may interfere with protocol (e.g., cardiovascular, gastrointestinal, neurological, known renal diseases (eGFR more than 60 mL/min), and/or diabetes) * Underwent bariatric surgery * Current enrolment in an exercise program or other intervention study * Planned a holiday during the intervention period and is unable to attend training sessions for more than 1 week

Design outcomes

Primary

MeasureTime frameDescription
Protein intakeThree monthsProtein intake
Appendicular lean massThree monthsAppendicular lean mass (DXA)

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026