Analgesia, Pain, Post Operative
Conditions
Keywords
laparoscopic cholecystectomy, oblique subcostal transversus abdominis plane block, external oblique interfascial plane block
Brief summary
Laparoscopic cholecystectomy (LC) surgery causes postoperative severe pain. As part of multimodal analgesia aimed at reducing postoperative opioid consumption and providing effective analgesia, ultrasound (US)-guided transversus abdominis plane block (TAP) and external oblique intercostal plane block (EOIPB) will be applied as regional anesthesia methods. There is no study in the literature comparing OSTAP and EOIP blocks, and our goal is to evaluate the analgesic effectiveness between OSTAP and EOIP blocks in LC surgeries.
Detailed description
Patients will be divided into two groups, and general anesthesia will be administered to all. Before extubation, one group will receive an external oblique intercostal nerve block, while the other group will receive an oblique subcostal transversus abdominis plane block. The randomization of the study will be carried out by a computer-generated randomization code (computer-generated) by a physician who will not be involved in patient follow-up. The interfascial plane block (either external oblique intercostal block or oblique subcostal block) will be provided to an anesthesiologist in a sealed envelope by an independent assistant staff member outside the study. The patient will not be aware of which block is applied. The anesthesiologist performing the block will not participate in the pain follow-up of the patients. Postoperative pain assessment and data collection will be conducted by another anesthesiologist unaware of the study. For standardization, the block procedure will be performed by an experienced anesthesiologist who has completed at least 20 previous successful and uncomplicated procedures.
Interventions
OTHEREOIP
Ultrasound guided External oblique intercostal block will be performed bilaterally.
OTHEROSTAP
Ultrasound guided oblique subcostal transversus abdominis plane block will be performed bilaterally.
Sponsors
Samsun University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Masking description
The anesthetist who will perform the blocks will not participate in the pain follow-up of the patients. Postoperative pain assessment and data collection will be performed by another anesthetist blinded to the study.
Intervention model description
two interventional group
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI \< 35 kg/m² Patients with ASA scores I and II
Exclusion criteria
* Patients who do not want to be included in the study Psychiatric and neurological disease with blurred consciousness Patients with ASA \> 3 BMI \> 35 kg/m² Abnormality in coagulation parameters History of allergy to local anesthetic drugs Infection at the injection site
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative opioid consumption | up to 24 hours | tramadol consumption in the first 24 hours after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| NRS scores | At 1,3, 6, 12, 18, 24 hours | NRS scores in the first 24 hours after surgery |
| Quality of recovery | 24 hours | QR15 scores |
| Nausea and vomiting | At 1,3, 6, 12, 18, 24 hours | Nausea and vomiting scores in the first 24 hours |
Countries
Turkey (Türkiye)
Outcome results
None listed