Free Fat Flap In Recurrent Neurogenic Thoracic Outlet Syndrome Surgical Treatment

Prospective Evaluation of Improvement in Pain and Quality of Life After Free Fat Flap for Treatment of Recurrent Neurological Thoracobrachial Outlet Syndrome

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06172101

Acronym

FIRST

Enrollment

Registered

2023-12-15

Start date

2023-12-18

Completion date

2026-05-18

Last updated

2024-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurogenic Thoracic Outlet Syndrome

Keywords

Recurrent neurogenic thoracic outlet syndrome, Free fat flap

Brief summary

The Thoraco-Brachial Outlet Syndrome (T-BOS) corresponds to the entirety of clinical manifestations related to the compression of the branches of the brachial plexus and/or the subclavian vessels during their passage through the cervico-thoracic region. Following surgery, a recurrence of symptoms occurs in 5% to 30% of operated patients. The treatment of these recurrences primarily relies on conservative therapies, and in case of failure, surgical intervention, particularly neurolysis of the brachial plexus. In order to prevent a new recurrence, it is desirable to cover the neurolyzed brachial plexus with a flap, providing better local vascularization. However, fatty perforating flaps, by avoiding muscle harvesting, reduce donor site sequelae. We aim to investigate, through validated and recommended questionnaires, the impact of covering the neurolyzed brachial plexus with a free fatty flap after neurolysis in the context of recurrent neurological Thoraco-Brachial Outlet Syndrome.

Interventions

OTHERFree fat flap

Free fat flap In Recurrent neurogenic thoracic outlet syndrome Surgical Treatment

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Patients underwent brachial plexus neurolysis and free fat flap coverage in the context of recurrence of neurological thoraco-brachial outlet syndrome

Exclusion criteria

* Patients were unable to express their non-opposition to participating in the study. * patients under guardianship or trusteeship. * patients whose mother tongue is not French. * patients who cannot read and/or write.

Design outcomes

Primary

Measure	Time frame	Description
Evaluating the impact on pain of covering the brachial plexus with a free fat flap	pre-op and six months post-op	the percentage reduction in pain assessed by a numerical scale from 0 to 10

Countries

France

Contacts

Primary ContactUgo Lancien, M.D

ugo.lancien@ch-nantes.fr+33 2 40 08 73 04

Backup ContactFrançois Thuau

francois.thuau@chu-nantes.fr+33 2 40 08 73 04

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026